Anti-INP4A/ INPP4A/ INPP4 monoclonal antibody

Anti-INP4A/ INPP4A/ INPP4 antibody for FACS & in-vivo assay

Target products collectionGo to INPP4A/INPP4A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0629-Ab-1/ GM-Tg-hg-MP0629-Ab-2Anti-Human INPP4A monoclonal antibodyHuman
GM-Tg-rg-MP0629-Ab-1/ GM-Tg-rg-MP0629-Ab-2Anti-Rat INPP4A monoclonal antibodyRat
GM-Tg-mg-MP0629-Ab-1/ GM-Tg-mg-MP0629-Ab-2Anti-Mouse INPP4A monoclonal antibodyMouse
GM-Tg-cynog-MP0629-Ab-1/ GM-Tg-cynog-MP0629-Ab-2Anti-Cynomolgus/ Rhesus macaque INPP4A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0629-Ab-1/ GM-Tg-felg-MP0629-Ab-2Anti-Feline INPP4A monoclonal antibodyFeline
GM-Tg-cang-MP0629-Ab-1/ GM-Tg-cang-MP0629-Ab-2Anti-Canine INPP4A monoclonal antibodyCanine
GM-Tg-bovg-MP0629-Ab-1/ GM-Tg-bovg-MP0629-Ab-2Anti-Bovine INPP4A monoclonal antibodyBovine
GM-Tg-equg-MP0629-Ab-1/ GM-Tg-equg-MP0629-Ab-2Anti-Equine INPP4A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0629-Ab-1/ GM-Tg-hg-MP0629-Ab-2; GM-Tg-rg-MP0629-Ab-1/ GM-Tg-rg-MP0629-Ab-2;
GM-Tg-mg-MP0629-Ab-1/ GM-Tg-mg-MP0629-Ab-2; GM-Tg-cynog-MP0629-Ab-1/ GM-Tg-cynog-MP0629-Ab-2;
GM-Tg-felg-MP0629-Ab-1/ GM-Tg-felg-MP0629-Ab-2; GM-Tg-cang-MP0629-Ab-1/ GM-Tg-cang-MP0629-Ab-2;
GM-Tg-bovg-MP0629-Ab-1/ GM-Tg-bovg-MP0629-Ab-2; GM-Tg-equg-MP0629-Ab-1/ GM-Tg-equg-MP0629-Ab-2
Products NameAnti-INPP4A monoclonal antibody
Formatmab
Target NameINPP4A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-INPP4A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species INP4A/ INPP4A/ INPP4 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0629
    Target NameINPP4A
    Gene ID3631,269180,80849,707986,474563,101088920,535487,100051038
    Gene Symbol and Synonyms107kDa,9630012D15,D130048C09Rik,INPP4,INPP4A,TVAS1
    Uniprot AccessionQ96PE3,Q62784
    Uniprot Entry NameINP4A_HUMAN,INP4A_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000040933
    Target ClassificationN/A

    The target: INPP4A, gene name: INPP4A, also named as INPP4, TVAS1. This gene encodes an Mg++ independent enzyme that hydrolyzes the 4-position phosphate from the inositol ring of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multiple transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.