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Anti-ITA7/ ITGA7 monoclonal antibody
Anti-ITA7/ ITGA7 antibody for FACS & in-vivo assay
Go to ITGA7/ITGA7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0635-Ab-1/ GM-Tg-hg-MP0635-Ab-2 | Anti-Human ITGA7 monoclonal antibody | Human |
| GM-Tg-rg-MP0635-Ab-1/ GM-Tg-rg-MP0635-Ab-2 | Anti-Rat ITGA7 monoclonal antibody | Rat |
| GM-Tg-mg-MP0635-Ab-1/ GM-Tg-mg-MP0635-Ab-2 | Anti-Mouse ITGA7 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0635-Ab-1/ GM-Tg-cynog-MP0635-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ITGA7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0635-Ab-1/ GM-Tg-felg-MP0635-Ab-2 | Anti-Feline ITGA7 monoclonal antibody | Feline |
| GM-Tg-cang-MP0635-Ab-1/ GM-Tg-cang-MP0635-Ab-2 | Anti-Canine ITGA7 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0635-Ab-1/ GM-Tg-bovg-MP0635-Ab-2 | Anti-Bovine ITGA7 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0635-Ab-1/ GM-Tg-equg-MP0635-Ab-2 | Anti-Equine ITGA7 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0635-Ab-1/ GM-Tg-hg-MP0635-Ab-2; GM-Tg-rg-MP0635-Ab-1/ GM-Tg-rg-MP0635-Ab-2; GM-Tg-mg-MP0635-Ab-1/ GM-Tg-mg-MP0635-Ab-2; GM-Tg-cynog-MP0635-Ab-1/ GM-Tg-cynog-MP0635-Ab-2; GM-Tg-felg-MP0635-Ab-1/ GM-Tg-felg-MP0635-Ab-2; GM-Tg-cang-MP0635-Ab-1/ GM-Tg-cang-MP0635-Ab-2; GM-Tg-bovg-MP0635-Ab-1/ GM-Tg-bovg-MP0635-Ab-2; GM-Tg-equg-MP0635-Ab-1/ GM-Tg-equg-MP0635-Ab-2 |
| Products Name | Anti-ITGA7 monoclonal antibody |
| Format | mab |
| Target Name | ITGA7 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ITGA7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Biosimilar | GMP-Bios-ab-005 | Pre-Made Abrilumab biosimilar, Whole mAb, Anti-α4β7/Integrin alpha 4 beta 7 Antibody: Anti-LPAM‑1 therapeutic antibody |
| Target Antigen | Products Developing | Multi-species ITA7/ ITGA7 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP0635 |
| Target Name | ITGA7 |
| Gene ID | 3679,16404,81008,707279,481097,101089783,506953,100058756 |
| Gene Symbol and Synonyms | alpha7,ITGA7,[a]7 |
| Uniprot Accession | Q13683,Q63258 |
| Uniprot Entry Name | ITA7_HUMAN,ITA7_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, INN Index |
| Disease | N/A |
| Gene Ensembl | ENSG00000135424 |
| Target Classification | N/A |
The target: ITGA7, gene name: ITGA7, also named as . The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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