Anti-ITA9/ ITGA9/ ALPHA-RLC monoclonal antibody

Anti-ITA9/ ITGA9/ ALPHA-RLC antibody for FACS & in-vivo assay

Target products collectionGo to ITGA9/ITGA9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0636-Ab-1/ GM-Tg-hg-MP0636-Ab-2Anti-Human ITGA9 monoclonal antibodyHuman
GM-Tg-rg-MP0636-Ab-1/ GM-Tg-rg-MP0636-Ab-2Anti-Rat ITGA9 monoclonal antibodyRat
GM-Tg-mg-MP0636-Ab-1/ GM-Tg-mg-MP0636-Ab-2Anti-Mouse ITGA9 monoclonal antibodyMouse
GM-Tg-cynog-MP0636-Ab-1/ GM-Tg-cynog-MP0636-Ab-2Anti-Cynomolgus/ Rhesus macaque ITGA9 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0636-Ab-1/ GM-Tg-felg-MP0636-Ab-2Anti-Feline ITGA9 monoclonal antibodyFeline
GM-Tg-cang-MP0636-Ab-1/ GM-Tg-cang-MP0636-Ab-2Anti-Canine ITGA9 monoclonal antibodyCanine
GM-Tg-bovg-MP0636-Ab-1/ GM-Tg-bovg-MP0636-Ab-2Anti-Bovine ITGA9 monoclonal antibodyBovine
GM-Tg-equg-MP0636-Ab-1/ GM-Tg-equg-MP0636-Ab-2Anti-Equine ITGA9 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0636-Ab-1/ GM-Tg-hg-MP0636-Ab-2; GM-Tg-rg-MP0636-Ab-1/ GM-Tg-rg-MP0636-Ab-2;
GM-Tg-mg-MP0636-Ab-1/ GM-Tg-mg-MP0636-Ab-2; GM-Tg-cynog-MP0636-Ab-1/ GM-Tg-cynog-MP0636-Ab-2;
GM-Tg-felg-MP0636-Ab-1/ GM-Tg-felg-MP0636-Ab-2; GM-Tg-cang-MP0636-Ab-1/ GM-Tg-cang-MP0636-Ab-2;
GM-Tg-bovg-MP0636-Ab-1/ GM-Tg-bovg-MP0636-Ab-2; GM-Tg-equg-MP0636-Ab-1/ GM-Tg-equg-MP0636-Ab-2
Products NameAnti-ITGA9 monoclonal antibody
Formatmab
Target NameITGA9
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ITGA9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ITA9/ ITGA9/ ALPHA-RLC VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0636
    Target NameITGA9
    Gene ID3680,104099,685004,106992270,477021,101090796,532127,100054374
    Gene Symbol and Synonyms(alpha)9,2610002H11Rik,6720458D17Rik,ALPHA-RLC,D130073C02,D9Ertd428e,ITGA4L,ITGA9,Itga9l,RLC
    Uniprot AccessionQ13797
    Uniprot Entry NameITA9_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000144668
    Target ClassificationN/A

    The target: ITGA9, gene name: ITGA9, also named as ALPHA-RLC, ITGA4L, RLC. This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.