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Anti-KCJ15/ KCNJ15/ IRKK monoclonal antibody
Anti-KCJ15/ KCNJ15/ IRKK antibody for FACS & in-vivo assay
Go to KCNJ15/KCNJ15 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0673-Ab-1/ GM-Tg-hg-MP0673-Ab-2 | Anti-Human KCNJ15 monoclonal antibody | Human |
| GM-Tg-rg-MP0673-Ab-1/ GM-Tg-rg-MP0673-Ab-2 | Anti-Rat KCNJ15 monoclonal antibody | Rat |
| GM-Tg-mg-MP0673-Ab-1/ GM-Tg-mg-MP0673-Ab-2 | Anti-Mouse KCNJ15 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0673-Ab-1/ GM-Tg-cynog-MP0673-Ab-2 | Anti-Cynomolgus/ Rhesus macaque KCNJ15 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0673-Ab-1/ GM-Tg-felg-MP0673-Ab-2 | Anti-Feline KCNJ15 monoclonal antibody | Feline |
| GM-Tg-cang-MP0673-Ab-1/ GM-Tg-cang-MP0673-Ab-2 | Anti-Canine KCNJ15 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0673-Ab-1/ GM-Tg-bovg-MP0673-Ab-2 | Anti-Bovine KCNJ15 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0673-Ab-1/ GM-Tg-equg-MP0673-Ab-2 | Anti-Equine KCNJ15 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0673-Ab-1/ GM-Tg-hg-MP0673-Ab-2; GM-Tg-rg-MP0673-Ab-1/ GM-Tg-rg-MP0673-Ab-2; GM-Tg-mg-MP0673-Ab-1/ GM-Tg-mg-MP0673-Ab-2; GM-Tg-cynog-MP0673-Ab-1/ GM-Tg-cynog-MP0673-Ab-2; GM-Tg-felg-MP0673-Ab-1/ GM-Tg-felg-MP0673-Ab-2; GM-Tg-cang-MP0673-Ab-1/ GM-Tg-cang-MP0673-Ab-2; GM-Tg-bovg-MP0673-Ab-1/ GM-Tg-bovg-MP0673-Ab-2; GM-Tg-equg-MP0673-Ab-1/ GM-Tg-equg-MP0673-Ab-2 |
| Products Name | Anti-KCNJ15 monoclonal antibody |
| Format | mab |
| Target Name | KCNJ15 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-KCNJ15 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species KCJ15/ KCNJ15/ IRKK VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLV000019 | human KCNJ15 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000019 | human KCNJ15 Lentivirus particle |
| ORF Viral Vector | pGMLPm001865 | mouse Kcnj15 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001865 | mouse Kcnj15 Lentivirus particle |
Target information
| Target ID | GM-MP0673 |
| Target Name | KCNJ15 |
| Gene ID | 3772,16516,170847,693427,487759,101100322,522184,100051634 |
| Gene Symbol and Synonyms | 4930414N08Rik,IRKK,KCNJ15,KIR1.3,KIR4.2 |
| Uniprot Accession | Q99712,Q91ZF1 |
| Uniprot Entry Name | KCJ15_HUMAN,KCJ15_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000157551 |
| Target Classification | Ion Channel |
The target: KCNJ15, gene name: KCNJ15, also named as IRKK, KIR1.3, KIR4.2. Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Eight transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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