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Anti-K0319/ KIAA0319/ AAVR monoclonal antibody
Anti-K0319/ KIAA0319/ AAVR antibody for FACS & in-vivo assay
Go to KIAA0319/KIAA0319 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0695-Ab-1/ GM-Tg-hg-MP0695-Ab-2 | Anti-Human KIAA0319 monoclonal antibody | Human |
| GM-Tg-rg-MP0695-Ab-1/ GM-Tg-rg-MP0695-Ab-2 | Anti-Rat KIAA0319 monoclonal antibody | Rat |
| GM-Tg-mg-MP0695-Ab-1/ GM-Tg-mg-MP0695-Ab-2 | Anti-Mouse KIAA0319 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0695-Ab-1/ GM-Tg-cynog-MP0695-Ab-2 | Anti-Cynomolgus/ Rhesus macaque KIAA0319 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0695-Ab-1/ GM-Tg-felg-MP0695-Ab-2 | Anti-Feline KIAA0319 monoclonal antibody | Feline |
| GM-Tg-cang-MP0695-Ab-1/ GM-Tg-cang-MP0695-Ab-2 | Anti-Canine KIAA0319 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0695-Ab-1/ GM-Tg-bovg-MP0695-Ab-2 | Anti-Bovine KIAA0319 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0695-Ab-1/ GM-Tg-equg-MP0695-Ab-2 | Anti-Equine KIAA0319 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0695-Ab-1/ GM-Tg-hg-MP0695-Ab-2; GM-Tg-rg-MP0695-Ab-1/ GM-Tg-rg-MP0695-Ab-2; GM-Tg-mg-MP0695-Ab-1/ GM-Tg-mg-MP0695-Ab-2; GM-Tg-cynog-MP0695-Ab-1/ GM-Tg-cynog-MP0695-Ab-2; GM-Tg-felg-MP0695-Ab-1/ GM-Tg-felg-MP0695-Ab-2; GM-Tg-cang-MP0695-Ab-1/ GM-Tg-cang-MP0695-Ab-2; GM-Tg-bovg-MP0695-Ab-1/ GM-Tg-bovg-MP0695-Ab-2; GM-Tg-equg-MP0695-Ab-1/ GM-Tg-equg-MP0695-Ab-2 |
| Products Name | Anti-KIAA0319 monoclonal antibody |
| Format | mab |
| Target Name | KIAA0319 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-KIAA0319 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species K0319/ KIAA0319/ AAVR VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP0695 |
| Target Name | KIAA0319 |
| Gene ID | 9856,210108,361244,715105,478736,101087992,520603,100067587 |
| Gene Symbol and Synonyms | 4930451E12Rik,AAVR,D130043K22Rik,DYLX2,DYX2,KIAA0319,NMIG,RGD1307443 |
| Uniprot Accession | Q5VV43,P0CI71 |
| Uniprot Entry Name | K0319_HUMAN,K0319_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000137261 |
| Target Classification | N/A |
The target: KIAA0319, gene name: KIAA0319, also named as AAVR, DYLX2, DYX2, NMIG. This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in this gene are associated with dyslexia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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