Anti-K319L/ KIAA0319L/ AAVR monoclonal antibody

Anti-K319L/ KIAA0319L/ AAVR antibody for FACS & in-vivo assay

Target products collectionGo to KIAA0319L/KIAA0319L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0696-Ab-1/ GM-Tg-hg-MP0696-Ab-2Anti-Human KIAA0319L monoclonal antibodyHuman
GM-Tg-rg-MP0696-Ab-1/ GM-Tg-rg-MP0696-Ab-2Anti-Rat KIAA0319L monoclonal antibodyRat
GM-Tg-mg-MP0696-Ab-1/ GM-Tg-mg-MP0696-Ab-2Anti-Mouse KIAA0319L monoclonal antibodyMouse
GM-Tg-cynog-MP0696-Ab-1/ GM-Tg-cynog-MP0696-Ab-2Anti-Cynomolgus/ Rhesus macaque KIAA0319L monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0696-Ab-1/ GM-Tg-felg-MP0696-Ab-2Anti-Feline KIAA0319L monoclonal antibodyFeline
GM-Tg-cang-MP0696-Ab-1/ GM-Tg-cang-MP0696-Ab-2Anti-Canine KIAA0319L monoclonal antibodyCanine
GM-Tg-bovg-MP0696-Ab-1/ GM-Tg-bovg-MP0696-Ab-2Anti-Bovine KIAA0319L monoclonal antibodyBovine
GM-Tg-equg-MP0696-Ab-1/ GM-Tg-equg-MP0696-Ab-2Anti-Equine KIAA0319L monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0696-Ab-1/ GM-Tg-hg-MP0696-Ab-2; GM-Tg-rg-MP0696-Ab-1/ GM-Tg-rg-MP0696-Ab-2;
GM-Tg-mg-MP0696-Ab-1/ GM-Tg-mg-MP0696-Ab-2; GM-Tg-cynog-MP0696-Ab-1/ GM-Tg-cynog-MP0696-Ab-2;
GM-Tg-felg-MP0696-Ab-1/ GM-Tg-felg-MP0696-Ab-2; GM-Tg-cang-MP0696-Ab-1/ GM-Tg-cang-MP0696-Ab-2;
GM-Tg-bovg-MP0696-Ab-1/ GM-Tg-bovg-MP0696-Ab-2; GM-Tg-equg-MP0696-Ab-1/ GM-Tg-equg-MP0696-Ab-2
Products NameAnti-KIAA0319L monoclonal antibody
Formatmab
Target NameKIAA0319L
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-KIAA0319L benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species K319L/ KIAA0319L/ AAVR VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0696
    Target NameKIAA0319L
    Gene ID79932,100317,100294508,712871,482483,101085992,784489,100055411
    Gene Symbol and SynonymsA730047D20Rik,AAVR,AAVRL,AU040320,KIAA0319L,LOC100294508
    Uniprot AccessionQ8IZA0
    Uniprot Entry NameK319L_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000142687
    Target ClassificationN/A

    The target: KIAA0319L, gene name: KIAA0319L, also named as AAVR, AAVRL. This gene is a candidate gene for dyslexia susceptibility.[provided by RefSeq, Apr 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.