Anti-ELAP1/ KIAA1324/ EIG121 monoclonal antibody

Anti-ELAP1/ KIAA1324/ EIG121 antibody for FACS & in-vivo assay

Target products collectionGo to KIAA1324/KIAA1324 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0698-Ab-1/ GM-Tg-hg-MP0698-Ab-2Anti-Human KIAA1324 monoclonal antibodyHuman
GM-Tg-rg-MP0698-Ab-1/ GM-Tg-rg-MP0698-Ab-2Anti-Rat KIAA1324 monoclonal antibodyRat
GM-Tg-mg-MP0698-Ab-1/ GM-Tg-mg-MP0698-Ab-2Anti-Mouse KIAA1324 monoclonal antibodyMouse
GM-Tg-cynog-MP0698-Ab-1/ GM-Tg-cynog-MP0698-Ab-2Anti-Cynomolgus/ Rhesus macaque KIAA1324 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0698-Ab-1/ GM-Tg-felg-MP0698-Ab-2Anti-Feline KIAA1324 monoclonal antibodyFeline
GM-Tg-cang-MP0698-Ab-1/ GM-Tg-cang-MP0698-Ab-2Anti-Canine KIAA1324 monoclonal antibodyCanine
GM-Tg-bovg-MP0698-Ab-1/ GM-Tg-bovg-MP0698-Ab-2Anti-Bovine KIAA1324 monoclonal antibodyBovine
GM-Tg-equg-MP0698-Ab-1/ GM-Tg-equg-MP0698-Ab-2Anti-Equine KIAA1324 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0698-Ab-1/ GM-Tg-hg-MP0698-Ab-2; GM-Tg-rg-MP0698-Ab-1/ GM-Tg-rg-MP0698-Ab-2;
GM-Tg-mg-MP0698-Ab-1/ GM-Tg-mg-MP0698-Ab-2; GM-Tg-cynog-MP0698-Ab-1/ GM-Tg-cynog-MP0698-Ab-2;
GM-Tg-felg-MP0698-Ab-1/ GM-Tg-felg-MP0698-Ab-2; GM-Tg-cang-MP0698-Ab-1/ GM-Tg-cang-MP0698-Ab-2;
GM-Tg-bovg-MP0698-Ab-1/ GM-Tg-bovg-MP0698-Ab-2; GM-Tg-equg-MP0698-Ab-1/ GM-Tg-equg-MP0698-Ab-2
Products NameAnti-KIAA1324 monoclonal antibody
Formatmab
Target NameKIAA1324
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-KIAA1324 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ELAP1/ KIAA1324/ EIG121 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0698
    Target NameKIAA1324
    Gene ID57535,229722,362019,479917,101097574,784449,100058066
    Gene Symbol and Synonyms5330417C22Rik,EIG121,ELAPOR1,Iir,Inceptor,KIAA1324,RGD1310209
    Uniprot AccessionQ6UXG2
    Uniprot Entry NameELAP1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000116299
    Target ClassificationN/A

    The target: KIAA1324, gene name: KIAA1324, also named as EIG121. Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.