Anti-K1549/ KIAA1549 monoclonal antibody

Anti-K1549/ KIAA1549 antibody for FACS & in-vivo assay

Target products collectionGo to KIAA1549/KIAA1549 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0701-Ab-1/ GM-Tg-hg-MP0701-Ab-2Anti-Human KIAA1549 monoclonal antibodyHuman
GM-Tg-rg-MP0701-Ab-1/ GM-Tg-rg-MP0701-Ab-2Anti-Rat KIAA1549 monoclonal antibodyRat
GM-Tg-mg-MP0701-Ab-1/ GM-Tg-mg-MP0701-Ab-2Anti-Mouse KIAA1549 monoclonal antibodyMouse
GM-Tg-cynog-MP0701-Ab-1/ GM-Tg-cynog-MP0701-Ab-2Anti-Cynomolgus/ Rhesus macaque KIAA1549 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0701-Ab-1/ GM-Tg-felg-MP0701-Ab-2Anti-Feline KIAA1549 monoclonal antibodyFeline
GM-Tg-cang-MP0701-Ab-1/ GM-Tg-cang-MP0701-Ab-2Anti-Canine KIAA1549 monoclonal antibodyCanine
GM-Tg-bovg-MP0701-Ab-1/ GM-Tg-bovg-MP0701-Ab-2Anti-Bovine KIAA1549 monoclonal antibodyBovine
GM-Tg-equg-MP0701-Ab-1/ GM-Tg-equg-MP0701-Ab-2Anti-Equine KIAA1549 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0701-Ab-1/ GM-Tg-hg-MP0701-Ab-2; GM-Tg-rg-MP0701-Ab-1/ GM-Tg-rg-MP0701-Ab-2;
GM-Tg-mg-MP0701-Ab-1/ GM-Tg-mg-MP0701-Ab-2; GM-Tg-cynog-MP0701-Ab-1/ GM-Tg-cynog-MP0701-Ab-2;
GM-Tg-felg-MP0701-Ab-1/ GM-Tg-felg-MP0701-Ab-2; GM-Tg-cang-MP0701-Ab-1/ GM-Tg-cang-MP0701-Ab-2;
GM-Tg-bovg-MP0701-Ab-1/ GM-Tg-bovg-MP0701-Ab-2; GM-Tg-equg-MP0701-Ab-1/ GM-Tg-equg-MP0701-Ab-2
Products NameAnti-KIAA1549 monoclonal antibody
Formatmab
Target NameKIAA1549
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-KIAA1549 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species K1549/ KIAA1549 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0701
    Target NameKIAA1549
    Gene ID57670,330286,312246,710668,482778,101089845,512679,100066648
    Gene Symbol and SynonymsD630045J12Rik,KIAA1549,mKIAA1549,RGD1306271,RP86
    Uniprot AccessionQ9HCM3
    Uniprot Entry NameK1549_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000122778
    Target ClassificationN/A

    The target: KIAA1549, gene name: KIAA1549, also named as . The protein encoded by this gene belongs to the UPF0606 family. This gene has been found to be fused to the BRAF oncogene in many cases of pilocytic astrocytoma. The fusion results from 2Mb tandem duplications at 7q34. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.