Anti-KLRD1/ CD94 monoclonal antibody

Anti-KLRD1/ CD94 antibody for FACS & in-vivo assay

Target products collectionGo to KLRD1/KLRD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0713-Ab-1/ GM-Tg-hg-MP0713-Ab-2Anti-Human KLRD1 monoclonal antibodyHuman
GM-Tg-rg-MP0713-Ab-1/ GM-Tg-rg-MP0713-Ab-2Anti-Rat KLRD1 monoclonal antibodyRat
GM-Tg-mg-MP0713-Ab-1/ GM-Tg-mg-MP0713-Ab-2Anti-Mouse KLRD1 monoclonal antibodyMouse
GM-Tg-cynog-MP0713-Ab-1/ GM-Tg-cynog-MP0713-Ab-2Anti-Cynomolgus/ Rhesus macaque KLRD1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0713-Ab-1/ GM-Tg-felg-MP0713-Ab-2Anti-Feline KLRD1 monoclonal antibodyFeline
GM-Tg-cang-MP0713-Ab-1/ GM-Tg-cang-MP0713-Ab-2Anti-Canine KLRD1 monoclonal antibodyCanine
GM-Tg-bovg-MP0713-Ab-1/ GM-Tg-bovg-MP0713-Ab-2Anti-Bovine KLRD1 monoclonal antibodyBovine
GM-Tg-equg-MP0713-Ab-1/ GM-Tg-equg-MP0713-Ab-2Anti-Equine KLRD1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0713-Ab-1/ GM-Tg-hg-MP0713-Ab-2; GM-Tg-rg-MP0713-Ab-1/ GM-Tg-rg-MP0713-Ab-2;
GM-Tg-mg-MP0713-Ab-1/ GM-Tg-mg-MP0713-Ab-2; GM-Tg-cynog-MP0713-Ab-1/ GM-Tg-cynog-MP0713-Ab-2;
GM-Tg-felg-MP0713-Ab-1/ GM-Tg-felg-MP0713-Ab-2; GM-Tg-cang-MP0713-Ab-1/ GM-Tg-cang-MP0713-Ab-2;
GM-Tg-bovg-MP0713-Ab-1/ GM-Tg-bovg-MP0713-Ab-2; GM-Tg-equg-MP0713-Ab-1/ GM-Tg-equg-MP0713-Ab-2
Products NameAnti-KLRD1 monoclonal antibody
Formatmab
Target NameKLRD1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-KLRD1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species KLRD1/ CD94 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0713
    Target NameKLRD1
    Gene ID3824,574145,611360,101086731,100062540
    Gene Symbol and SynonymsCD94,CD94-B,KLRD1
    Uniprot AccessionQ13241,Q9MZK9,Q38HS3
    Uniprot Entry NameKLRD1_HUMAN,KLRD1_MACMU,KLRD1_CANLF
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000134539
    Target ClassificationN/A

    The target: KLRD1, gene name: KLRD1, also named as CD94. Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.