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Anti-PLPR4/ PLPPR4/ LPPR4 monoclonal antibody
Anti-PLPR4/ PLPPR4/ LPPR4 antibody for FACS & in-vivo assay
Go to PLPPR4/PLPPR4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0742-Ab-1/ GM-Tg-hg-MP0742-Ab-2 | Anti-Human PLPPR4 monoclonal antibody | Human |
| GM-Tg-rg-MP0742-Ab-1/ GM-Tg-rg-MP0742-Ab-2 | Anti-Rat PLPPR4 monoclonal antibody | Rat |
| GM-Tg-mg-MP0742-Ab-1/ GM-Tg-mg-MP0742-Ab-2 | Anti-Mouse PLPPR4 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0742-Ab-1/ GM-Tg-cynog-MP0742-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PLPPR4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0742-Ab-1/ GM-Tg-felg-MP0742-Ab-2 | Anti-Feline PLPPR4 monoclonal antibody | Feline |
| GM-Tg-cang-MP0742-Ab-1/ GM-Tg-cang-MP0742-Ab-2 | Anti-Canine PLPPR4 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0742-Ab-1/ GM-Tg-bovg-MP0742-Ab-2 | Anti-Bovine PLPPR4 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0742-Ab-1/ GM-Tg-equg-MP0742-Ab-2 | Anti-Equine PLPPR4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0742-Ab-1/ GM-Tg-hg-MP0742-Ab-2; GM-Tg-rg-MP0742-Ab-1/ GM-Tg-rg-MP0742-Ab-2; GM-Tg-mg-MP0742-Ab-1/ GM-Tg-mg-MP0742-Ab-2; GM-Tg-cynog-MP0742-Ab-1/ GM-Tg-cynog-MP0742-Ab-2; GM-Tg-felg-MP0742-Ab-1/ GM-Tg-felg-MP0742-Ab-2; GM-Tg-cang-MP0742-Ab-1/ GM-Tg-cang-MP0742-Ab-2; GM-Tg-bovg-MP0742-Ab-1/ GM-Tg-bovg-MP0742-Ab-2; GM-Tg-equg-MP0742-Ab-1/ GM-Tg-equg-MP0742-Ab-2 |
| Products Name | Anti-PLPPR4 monoclonal antibody |
| Format | mab |
| Target Name | PLPPR4 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PLPPR4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PLPR4/ PLPPR4/ LPPR4 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMAAV000367 | human PLPPR4 AAV plasmid |
| ORF Viral Vector | vGMAAV000367 | human PLPPR4 AAV particle |
Target information
| Target ID | GM-MP0742 |
| Target Name | PLPPR4 |
| Gene ID | 9890,229791,295401,716103,490146,100169701,513388,100050850 |
| Gene Symbol and Synonyms | A330086D10,D3Bwg0562e,LPPR4,LPR4,mKIAA0455,PHP1,PLPPR4,PRG-1,PRG1 |
| Uniprot Accession | Q7Z2D5,Q7™B7 |
| Uniprot Entry Name | PLPR4_HUMAN,PLPR4_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000117600 |
| Target Classification | N/A |
The target: PLPPR4, gene name: PLPPR4, also named as LPPR4, LPR4, PHP1, PRG-1, PRG1. The protein encoded by this gene belongs to the lipid phosphate phosphatase (LPP) family. LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions. This protein is specifically expressed in neurons. It is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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