Anti-LRIG1/ LIG-1/ LIG1 monoclonal antibody

Anti-LRIG1/ LIG-1/ LIG1 antibody for FACS & in-vivo assay

Target products collectionGo to LRIG1/LRIG1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0749-Ab-1/ GM-Tg-hg-MP0749-Ab-2Anti-Human LRIG1 monoclonal antibodyHuman
GM-Tg-rg-MP0749-Ab-1/ GM-Tg-rg-MP0749-Ab-2Anti-Rat LRIG1 monoclonal antibodyRat
GM-Tg-mg-MP0749-Ab-1/ GM-Tg-mg-MP0749-Ab-2Anti-Mouse LRIG1 monoclonal antibodyMouse
GM-Tg-cynog-MP0749-Ab-1/ GM-Tg-cynog-MP0749-Ab-2Anti-Cynomolgus/ Rhesus macaque LRIG1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0749-Ab-1/ GM-Tg-felg-MP0749-Ab-2Anti-Feline LRIG1 monoclonal antibodyFeline
GM-Tg-cang-MP0749-Ab-1/ GM-Tg-cang-MP0749-Ab-2Anti-Canine LRIG1 monoclonal antibodyCanine
GM-Tg-bovg-MP0749-Ab-1/ GM-Tg-bovg-MP0749-Ab-2Anti-Bovine LRIG1 monoclonal antibodyBovine
GM-Tg-equg-MP0749-Ab-1/ GM-Tg-equg-MP0749-Ab-2Anti-Equine LRIG1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0749-Ab-1/ GM-Tg-hg-MP0749-Ab-2; GM-Tg-rg-MP0749-Ab-1/ GM-Tg-rg-MP0749-Ab-2;
GM-Tg-mg-MP0749-Ab-1/ GM-Tg-mg-MP0749-Ab-2; GM-Tg-cynog-MP0749-Ab-1/ GM-Tg-cynog-MP0749-Ab-2;
GM-Tg-felg-MP0749-Ab-1/ GM-Tg-felg-MP0749-Ab-2; GM-Tg-cang-MP0749-Ab-1/ GM-Tg-cang-MP0749-Ab-2;
GM-Tg-bovg-MP0749-Ab-1/ GM-Tg-bovg-MP0749-Ab-2; GM-Tg-equg-MP0749-Ab-1/ GM-Tg-equg-MP0749-Ab-2
Products NameAnti-LRIG1 monoclonal antibody
Formatmab
Target NameLRIG1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-LRIG1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species LRIG1/ LIG-1/ LIG1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0749
    Target NameLRIG1
    Gene ID26018,16206,312574,700033,484698,101087908,505750,100064196
    Gene Symbol and SynonymsD6Bwg0781e,Img,LIG-1,LIG1,LRIG1
    Uniprot AccessionQ96JA1
    Uniprot Entry NameLRIG1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseCancer
    Gene EnsemblENSG00000144749
    Target ClassificationTumor-associated antigen (TAA)

    The target: LRIG1, gene name: LRIG1, also named as LIG-1, LIG1. Predicted to act upstream of or within several processes, including innervation; otolith morphogenesis; and sensory perception of sound. Predicted to be located in plasma membrane. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.