Anti-LRIG3/ LIG3 monoclonal antibody

Anti-LRIG3/ LIG3 antibody for FACS & in-vivo assay

Target products collectionGo to LRIG3/LRIG3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0751-Ab-1/ GM-Tg-hg-MP0751-Ab-2Anti-Human LRIG3 monoclonal antibodyHuman
GM-Tg-rg-MP0751-Ab-1/ GM-Tg-rg-MP0751-Ab-2Anti-Rat LRIG3 monoclonal antibodyRat
GM-Tg-mg-MP0751-Ab-1/ GM-Tg-mg-MP0751-Ab-2Anti-Mouse LRIG3 monoclonal antibodyMouse
GM-Tg-cynog-MP0751-Ab-1/ GM-Tg-cynog-MP0751-Ab-2Anti-Cynomolgus/ Rhesus macaque LRIG3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0751-Ab-1/ GM-Tg-felg-MP0751-Ab-2Anti-Feline LRIG3 monoclonal antibodyFeline
GM-Tg-cang-MP0751-Ab-1/ GM-Tg-cang-MP0751-Ab-2Anti-Canine LRIG3 monoclonal antibodyCanine
GM-Tg-bovg-MP0751-Ab-1/ GM-Tg-bovg-MP0751-Ab-2Anti-Bovine LRIG3 monoclonal antibodyBovine
GM-Tg-equg-MP0751-Ab-1/ GM-Tg-equg-MP0751-Ab-2Anti-Equine LRIG3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0751-Ab-1/ GM-Tg-hg-MP0751-Ab-2; GM-Tg-rg-MP0751-Ab-1/ GM-Tg-rg-MP0751-Ab-2;
GM-Tg-mg-MP0751-Ab-1/ GM-Tg-mg-MP0751-Ab-2; GM-Tg-cynog-MP0751-Ab-1/ GM-Tg-cynog-MP0751-Ab-2;
GM-Tg-felg-MP0751-Ab-1/ GM-Tg-felg-MP0751-Ab-2; GM-Tg-cang-MP0751-Ab-1/ GM-Tg-cang-MP0751-Ab-2;
GM-Tg-bovg-MP0751-Ab-1/ GM-Tg-bovg-MP0751-Ab-2; GM-Tg-equg-MP0751-Ab-1/ GM-Tg-equg-MP0751-Ab-2
Products NameAnti-LRIG3 monoclonal antibody
Formatmab
Target NameLRIG3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-LRIG3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species LRIG3/ LIG3 VLP (virus-like particle) (Products Developing)
    CytokineGM-Tg-g-MP0751-Ag-1leucine-rich repeats and immunoglobulin-like domains 3 (LRIG3) protein


    Target information

    Target IDGM-MP0751
    Target NameLRIG3
    Gene ID121227,320398,299830,716344,474423,101083861,506574,100054709
    Gene Symbol and Synonyms9030421L11Rik,9130004I02Rik,9430095K15Rik,LIG3,LRIG3,mKIAA3016,RGD1561255
    Uniprot AccessionQ6UXM1
    Uniprot Entry NameLRIG3_HUMAN
    Protein Sub-locationTransmembrane Protein
    CategoryCytokine Target
    DiseaseLung Cancer
    Gene EnsemblENSG00000139263
    Target ClassificationN/A

    The target: LRIG3, gene name: LRIG3, also named as LIG3. Predicted to act upstream of or within otolith morphogenesis. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.