Anti-IRAG2/ LRMP/ JAW1 monoclonal antibody

Anti-IRAG2/ LRMP/ JAW1 antibody for FACS & in-vivo assay

Target products collectionGo to LRMP/LRMP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0752-Ab-1/ GM-Tg-hg-MP0752-Ab-2Anti-Human LRMP monoclonal antibodyHuman
GM-Tg-rg-MP0752-Ab-1/ GM-Tg-rg-MP0752-Ab-2Anti-Rat LRMP monoclonal antibodyRat
GM-Tg-mg-MP0752-Ab-1/ GM-Tg-mg-MP0752-Ab-2Anti-Mouse LRMP monoclonal antibodyMouse
GM-Tg-cynog-MP0752-Ab-1/ GM-Tg-cynog-MP0752-Ab-2Anti-Cynomolgus/ Rhesus macaque LRMP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0752-Ab-1/ GM-Tg-felg-MP0752-Ab-2Anti-Feline LRMP monoclonal antibodyFeline
GM-Tg-cang-MP0752-Ab-1/ GM-Tg-cang-MP0752-Ab-2Anti-Canine LRMP monoclonal antibodyCanine
GM-Tg-bovg-MP0752-Ab-1/ GM-Tg-bovg-MP0752-Ab-2Anti-Bovine LRMP monoclonal antibodyBovine
GM-Tg-equg-MP0752-Ab-1/ GM-Tg-equg-MP0752-Ab-2Anti-Equine LRMP monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0752-Ab-1/ GM-Tg-hg-MP0752-Ab-2; GM-Tg-rg-MP0752-Ab-1/ GM-Tg-rg-MP0752-Ab-2;
GM-Tg-mg-MP0752-Ab-1/ GM-Tg-mg-MP0752-Ab-2; GM-Tg-cynog-MP0752-Ab-1/ GM-Tg-cynog-MP0752-Ab-2;
GM-Tg-felg-MP0752-Ab-1/ GM-Tg-felg-MP0752-Ab-2; GM-Tg-cang-MP0752-Ab-1/ GM-Tg-cang-MP0752-Ab-2;
GM-Tg-bovg-MP0752-Ab-1/ GM-Tg-bovg-MP0752-Ab-2; GM-Tg-equg-MP0752-Ab-1/ GM-Tg-equg-MP0752-Ab-2
Products NameAnti-LRMP monoclonal antibody
Formatmab
Target NameLRMP
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-LRMP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species IRAG2/ LRMP/ JAW1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0752
    Target NameLRMP
    Gene ID4033,16970,500361,707643,486631,101099475,100140494,100068768
    Gene Symbol and SynonymsD6Int3,D6Int4,D6Int5,D6Int7,D6Int8,IRAG2,JAW1,LRMP,RGD1562062
    Uniprot AccessionQ12912
    Uniprot Entry NameIRAG2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000118308
    Target ClassificationN/A

    The target: LRMP, gene name: LRMP, also named as JAW1. The protein encode dby this gene is expressed in a developmentally regulated manner in lymphoid cell lines and tissues. The protein is localized to the cytoplasmic face of the endoplasmic reticulum. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.