Anti-LRP10/ LRP-10/ LRP9 monoclonal antibody

Anti-LRP10/ LRP-10/ LRP9 antibody for FACS & in-vivo assay

Target products collectionGo to LRP10/LRP10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0753-Ab-1/ GM-Tg-hg-MP0753-Ab-2Anti-Human LRP10 monoclonal antibodyHuman
GM-Tg-rg-MP0753-Ab-1/ GM-Tg-rg-MP0753-Ab-2Anti-Rat LRP10 monoclonal antibodyRat
GM-Tg-mg-MP0753-Ab-1/ GM-Tg-mg-MP0753-Ab-2Anti-Mouse LRP10 monoclonal antibodyMouse
GM-Tg-cynog-MP0753-Ab-1/ GM-Tg-cynog-MP0753-Ab-2Anti-Cynomolgus/ Rhesus macaque LRP10 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0753-Ab-1/ GM-Tg-felg-MP0753-Ab-2Anti-Feline LRP10 monoclonal antibodyFeline
GM-Tg-cang-MP0753-Ab-1/ GM-Tg-cang-MP0753-Ab-2Anti-Canine LRP10 monoclonal antibodyCanine
GM-Tg-bovg-MP0753-Ab-1/ GM-Tg-bovg-MP0753-Ab-2Anti-Bovine LRP10 monoclonal antibodyBovine
GM-Tg-equg-MP0753-Ab-1/ GM-Tg-equg-MP0753-Ab-2Anti-Equine LRP10 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0753-Ab-1/ GM-Tg-hg-MP0753-Ab-2; GM-Tg-rg-MP0753-Ab-1/ GM-Tg-rg-MP0753-Ab-2;
GM-Tg-mg-MP0753-Ab-1/ GM-Tg-mg-MP0753-Ab-2; GM-Tg-cynog-MP0753-Ab-1/ GM-Tg-cynog-MP0753-Ab-2;
GM-Tg-felg-MP0753-Ab-1/ GM-Tg-felg-MP0753-Ab-2; GM-Tg-cang-MP0753-Ab-1/ GM-Tg-cang-MP0753-Ab-2;
GM-Tg-bovg-MP0753-Ab-1/ GM-Tg-bovg-MP0753-Ab-2; GM-Tg-equg-MP0753-Ab-1/ GM-Tg-equg-MP0753-Ab-2
Products NameAnti-LRP10 monoclonal antibody
Formatmab
Target NameLRP10
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-LRP10 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species LRP10/ LRP-10/ LRP9 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0753
    Target NameLRP10
    Gene ID26020,65107,305880,712506,608002,101090021,515494,100052839
    Gene Symbol and SynonymsLRP-10,LRP10,LRP9,MST087,MSTP087
    Uniprot AccessionQ7Z4F1
    Uniprot Entry NameLRP10_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000197324
    Target ClassificationN/A

    The target: LRP10, gene name: LRP10, also named as LRP-10, LRP9, MST087, MSTP087. This gene encodes a low density lipoprotein receptor family protein. A similar protein in mouse is thought to play a role in the uptake of apolipoprotein E-containing lipoproteins. [provided by RefSeq, Jul 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.