Anti-LRP11/ MANSC3/ bA350J20.3 monoclonal antibody

Anti-LRP11/ MANSC3/ bA350J20.3 antibody for FACS & in-vivo assay

Target products collectionGo to LRP11/LRP11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0754-Ab-1/ GM-Tg-hg-MP0754-Ab-2Anti-Human LRP11 monoclonal antibodyHuman
GM-Tg-rg-MP0754-Ab-1/ GM-Tg-rg-MP0754-Ab-2Anti-Rat LRP11 monoclonal antibodyRat
GM-Tg-mg-MP0754-Ab-1/ GM-Tg-mg-MP0754-Ab-2Anti-Mouse LRP11 monoclonal antibodyMouse
GM-Tg-cynog-MP0754-Ab-1/ GM-Tg-cynog-MP0754-Ab-2Anti-Cynomolgus/ Rhesus macaque LRP11 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0754-Ab-1/ GM-Tg-felg-MP0754-Ab-2Anti-Feline LRP11 monoclonal antibodyFeline
GM-Tg-cang-MP0754-Ab-1/ GM-Tg-cang-MP0754-Ab-2Anti-Canine LRP11 monoclonal antibodyCanine
GM-Tg-bovg-MP0754-Ab-1/ GM-Tg-bovg-MP0754-Ab-2Anti-Bovine LRP11 monoclonal antibodyBovine
GM-Tg-equg-MP0754-Ab-1/ GM-Tg-equg-MP0754-Ab-2Anti-Equine LRP11 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0754-Ab-1/ GM-Tg-hg-MP0754-Ab-2; GM-Tg-rg-MP0754-Ab-1/ GM-Tg-rg-MP0754-Ab-2;
GM-Tg-mg-MP0754-Ab-1/ GM-Tg-mg-MP0754-Ab-2; GM-Tg-cynog-MP0754-Ab-1/ GM-Tg-cynog-MP0754-Ab-2;
GM-Tg-felg-MP0754-Ab-1/ GM-Tg-felg-MP0754-Ab-2; GM-Tg-cang-MP0754-Ab-1/ GM-Tg-cang-MP0754-Ab-2;
GM-Tg-bovg-MP0754-Ab-1/ GM-Tg-bovg-MP0754-Ab-2; GM-Tg-equg-MP0754-Ab-1/ GM-Tg-equg-MP0754-Ab-2
Products NameAnti-LRP11 monoclonal antibody
Formatmab
Target NameLRP11
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-LRP11 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species LRP11/ MANSC3/ bA350J20.3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0754
    Target NameLRP11
    Gene ID84918,237253,292462,697652,100688818,101081983,617450,100064498
    Gene Symbol and Synonyms1700034J19Rik,6330533B21,9830160H19Rik,bA350J20.3,LRP11,MANSC3
    Uniprot AccessionQ86VZ4
    Uniprot Entry NameLRP11_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000120256
    Target ClassificationN/A

    The target: LRP11, gene name: LRP11, also named as MANSC3, bA350J20.3. Enables phosphoprotein binding activity. Predicted to act upstream of or within several processes, including response to cold; response to immobilization stress; and response to water deprivation. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.