Anti-LRC4C/ LRRC4C/ NGL-1 monoclonal antibody

Anti-LRC4C/ LRRC4C/ NGL-1 antibody for FACS & in-vivo assay

Target products collectionGo to LRRC4C/LRRC4C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0764-Ab-1/ GM-Tg-hg-MP0764-Ab-2Anti-Human LRRC4C monoclonal antibodyHuman
GM-Tg-rg-MP0764-Ab-1/ GM-Tg-rg-MP0764-Ab-2Anti-Rat LRRC4C monoclonal antibodyRat
GM-Tg-mg-MP0764-Ab-1/ GM-Tg-mg-MP0764-Ab-2Anti-Mouse LRRC4C monoclonal antibodyMouse
GM-Tg-cynog-MP0764-Ab-1/ GM-Tg-cynog-MP0764-Ab-2Anti-Cynomolgus/ Rhesus macaque LRRC4C monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0764-Ab-1/ GM-Tg-felg-MP0764-Ab-2Anti-Feline LRRC4C monoclonal antibodyFeline
GM-Tg-cang-MP0764-Ab-1/ GM-Tg-cang-MP0764-Ab-2Anti-Canine LRRC4C monoclonal antibodyCanine
GM-Tg-bovg-MP0764-Ab-1/ GM-Tg-bovg-MP0764-Ab-2Anti-Bovine LRRC4C monoclonal antibodyBovine
GM-Tg-equg-MP0764-Ab-1/ GM-Tg-equg-MP0764-Ab-2Anti-Equine LRRC4C monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0764-Ab-1/ GM-Tg-hg-MP0764-Ab-2; GM-Tg-rg-MP0764-Ab-1/ GM-Tg-rg-MP0764-Ab-2;
GM-Tg-mg-MP0764-Ab-1/ GM-Tg-mg-MP0764-Ab-2; GM-Tg-cynog-MP0764-Ab-1/ GM-Tg-cynog-MP0764-Ab-2;
GM-Tg-felg-MP0764-Ab-1/ GM-Tg-felg-MP0764-Ab-2; GM-Tg-cang-MP0764-Ab-1/ GM-Tg-cang-MP0764-Ab-2;
GM-Tg-bovg-MP0764-Ab-1/ GM-Tg-bovg-MP0764-Ab-2; GM-Tg-equg-MP0764-Ab-1/ GM-Tg-equg-MP0764-Ab-2
Products NameAnti-LRRC4C monoclonal antibody
Formatmab
Target NameLRRC4C
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-LRRC4C benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species LRC4C/ LRRC4C/ NGL-1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0764
    Target NameLRRC4C
    Gene ID57689,241568,311236,716620,483417,101097020,112441487,100049944
    Gene Symbol and Synonyms6430556C10Rik,LRRC4C,NGL-1,NGL1,RGD1311013
    Uniprot AccessionQ9HCJ2
    Uniprot Entry NameLRC4C_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000148948
    Target ClassificationN/A

    The target: LRRC4C, gene name: LRRC4C, also named as NGL-1, NGL1. NGL1 is a specific binding partner for netrin G1 (NTNG1; MIM 608818), which is a member of the netrin family of axon guidance molecules (Lin et al., 2003 [PubMed 14595443]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.