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Anti-MAGT1/ IAP/ MRX95 monoclonal antibody
Anti-MAGT1/ IAP/ MRX95 antibody for FACS & in-vivo assay
Go to MAGT1/MAGT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0793-Ab-1/ GM-Tg-hg-MP0793-Ab-2 | Anti-Human MAGT1 monoclonal antibody | Human |
| GM-Tg-rg-MP0793-Ab-1/ GM-Tg-rg-MP0793-Ab-2 | Anti-Rat MAGT1 monoclonal antibody | Rat |
| GM-Tg-mg-MP0793-Ab-1/ GM-Tg-mg-MP0793-Ab-2 | Anti-Mouse MAGT1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0793-Ab-1/ GM-Tg-cynog-MP0793-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MAGT1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0793-Ab-1/ GM-Tg-felg-MP0793-Ab-2 | Anti-Feline MAGT1 monoclonal antibody | Feline |
| GM-Tg-cang-MP0793-Ab-1/ GM-Tg-cang-MP0793-Ab-2 | Anti-Canine MAGT1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0793-Ab-1/ GM-Tg-bovg-MP0793-Ab-2 | Anti-Bovine MAGT1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0793-Ab-1/ GM-Tg-equg-MP0793-Ab-2 | Anti-Equine MAGT1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0793-Ab-1/ GM-Tg-hg-MP0793-Ab-2; GM-Tg-rg-MP0793-Ab-1/ GM-Tg-rg-MP0793-Ab-2; GM-Tg-mg-MP0793-Ab-1/ GM-Tg-mg-MP0793-Ab-2; GM-Tg-cynog-MP0793-Ab-1/ GM-Tg-cynog-MP0793-Ab-2; GM-Tg-felg-MP0793-Ab-1/ GM-Tg-felg-MP0793-Ab-2; GM-Tg-cang-MP0793-Ab-1/ GM-Tg-cang-MP0793-Ab-2; GM-Tg-bovg-MP0793-Ab-1/ GM-Tg-bovg-MP0793-Ab-2; GM-Tg-equg-MP0793-Ab-1/ GM-Tg-equg-MP0793-Ab-2 |
| Products Name | Anti-MAGT1 monoclonal antibody |
| Format | mab |
| Target Name | MAGT1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MAGT1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species MAGT1/ IAP/ MRX95 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLPm001599 | mouse Magt1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001599 | mouse Magt1 Lentivirus particle |
Target information
| Target ID | GM-MP0793 |
| Target Name | MAGT1 |
| Gene ID | 84061,67075,116967,710098,491975,101085275,100301169,100071782 |
| Gene Symbol and Synonyms | 2410001C15Rik,2610529C04Rik,2810482I07Rik,bA217H1.1,CDG1CC,IAG2,IAP,MAGT1,MRX95,OST3B,PRO0756,SLC58A1,XMEN |
| Uniprot Accession | Q9H0U3,O35777 |
| Uniprot Entry Name | MAGT1_HUMAN,MAGT1_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000102158 |
| Target Classification | N/A |
The target: MAGT1, gene name: MAGT1, also named as IAP, MRX95, OST3B, PRO0756, XMEN, bA217H1.1. This gene encodes a ubiquitously expressed magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause a form of X-linked intellectual disability (XLID). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29. [provided by RefSeq, Jul 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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