Anti-MALL/ BENE monoclonal antibody

Anti-MALL/ BENE antibody for FACS & in-vivo assay

Target products collectionGo to MALL/MALL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0794-Ab-1/ GM-Tg-hg-MP0794-Ab-2Anti-Human MALL monoclonal antibodyHuman
GM-Tg-rg-MP0794-Ab-1/ GM-Tg-rg-MP0794-Ab-2Anti-Rat MALL monoclonal antibodyRat
GM-Tg-mg-MP0794-Ab-1/ GM-Tg-mg-MP0794-Ab-2Anti-Mouse MALL monoclonal antibodyMouse
GM-Tg-cynog-MP0794-Ab-1/ GM-Tg-cynog-MP0794-Ab-2Anti-Cynomolgus/ Rhesus macaque MALL monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0794-Ab-1/ GM-Tg-felg-MP0794-Ab-2Anti-Feline MALL monoclonal antibodyFeline
GM-Tg-cang-MP0794-Ab-1/ GM-Tg-cang-MP0794-Ab-2Anti-Canine MALL monoclonal antibodyCanine
GM-Tg-bovg-MP0794-Ab-1/ GM-Tg-bovg-MP0794-Ab-2Anti-Bovine MALL monoclonal antibodyBovine
GM-Tg-equg-MP0794-Ab-1/ GM-Tg-equg-MP0794-Ab-2Anti-Equine MALL monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0794-Ab-1/ GM-Tg-hg-MP0794-Ab-2; GM-Tg-rg-MP0794-Ab-1/ GM-Tg-rg-MP0794-Ab-2;
GM-Tg-mg-MP0794-Ab-1/ GM-Tg-mg-MP0794-Ab-2; GM-Tg-cynog-MP0794-Ab-1/ GM-Tg-cynog-MP0794-Ab-2;
GM-Tg-felg-MP0794-Ab-1/ GM-Tg-felg-MP0794-Ab-2; GM-Tg-cang-MP0794-Ab-1/ GM-Tg-cang-MP0794-Ab-2;
GM-Tg-bovg-MP0794-Ab-1/ GM-Tg-bovg-MP0794-Ab-2; GM-Tg-equg-MP0794-Ab-1/ GM-Tg-equg-MP0794-Ab-2
Products NameAnti-MALL monoclonal antibody
Formatmab
Target NameMALL
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MALL benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MALL/ BENE VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0794
    Target NameMALL
    Gene ID7851,228576,362211,696102,483056,101085541,512289,100063854
    Gene Symbol and SynonymsBENE,MALL,RGD1310869
    Uniprot AccessionQ13021
    Uniprot Entry NameMALL_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseCancer
    Gene EnsemblENSG00000144063
    Target ClassificationTumor-associated antigen (TAA)

    The target: MALL, gene name: MALL, also named as BENE. This gene encodes an element of the machinery for raft-mediated trafficking in endothelial cells. The encoded protein, a member of the MAL proteolipid family, predominantly localizes in glycolipid- and cholesterol-enriched membrane (GEM) rafts. It interacts with caveolin-1. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.