Anti-MEP1A/ PPHA monoclonal antibody

Anti-MEP1A/ PPHA antibody for FACS & in-vivo assay

Target products collectionGo to MEP1A/MEP1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0805-Ab-1/ GM-Tg-hg-MP0805-Ab-2Anti-Human MEP1A monoclonal antibodyHuman
GM-Tg-rg-MP0805-Ab-1/ GM-Tg-rg-MP0805-Ab-2Anti-Rat MEP1A monoclonal antibodyRat
GM-Tg-mg-MP0805-Ab-1/ GM-Tg-mg-MP0805-Ab-2Anti-Mouse MEP1A monoclonal antibodyMouse
GM-Tg-cynog-MP0805-Ab-1/ GM-Tg-cynog-MP0805-Ab-2Anti-Cynomolgus/ Rhesus macaque MEP1A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0805-Ab-1/ GM-Tg-felg-MP0805-Ab-2Anti-Feline MEP1A monoclonal antibodyFeline
GM-Tg-cang-MP0805-Ab-1/ GM-Tg-cang-MP0805-Ab-2Anti-Canine MEP1A monoclonal antibodyCanine
GM-Tg-bovg-MP0805-Ab-1/ GM-Tg-bovg-MP0805-Ab-2Anti-Bovine MEP1A monoclonal antibodyBovine
GM-Tg-equg-MP0805-Ab-1/ GM-Tg-equg-MP0805-Ab-2Anti-Equine MEP1A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0805-Ab-1/ GM-Tg-hg-MP0805-Ab-2; GM-Tg-rg-MP0805-Ab-1/ GM-Tg-rg-MP0805-Ab-2;
GM-Tg-mg-MP0805-Ab-1/ GM-Tg-mg-MP0805-Ab-2; GM-Tg-cynog-MP0805-Ab-1/ GM-Tg-cynog-MP0805-Ab-2;
GM-Tg-felg-MP0805-Ab-1/ GM-Tg-felg-MP0805-Ab-2; GM-Tg-cang-MP0805-Ab-1/ GM-Tg-cang-MP0805-Ab-2;
GM-Tg-bovg-MP0805-Ab-1/ GM-Tg-bovg-MP0805-Ab-2; GM-Tg-equg-MP0805-Ab-1/ GM-Tg-equg-MP0805-Ab-2
Products NameAnti-MEP1A monoclonal antibody
Formatmab
Target NameMEP1A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MEP1A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MEP1A/ PPHA VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0805
    Target NameMEP1A
    Gene ID4224,17287,25684,704781,481826,101101056,513936,100068383
    Gene Symbol and SynonymsMep-1,Mep-1a,Mep1,MEP1A,PPHA
    Uniprot AccessionQ16819,Q64230
    Uniprot Entry NameMEP1A_HUMAN,MEP1A_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseMucocutaneous lymph node syndrome [Kawasaki]
    Gene EnsemblENSG00000112818
    Target ClassificationN/A

    The target: MEP1A, gene name: MEP1A, also named as PPHA. Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Located in extracellular exosome. Part of meprin A complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.