Anti-MICA3/ MICAL3/ MICAL-3 monoclonal antibody

Anti-MICA3/ MICAL3/ MICAL-3 antibody for FACS & in-vivo assay

Target products collectionGo to MICAL3/MICAL3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0813-Ab-1/ GM-Tg-hg-MP0813-Ab-2Anti-Human MICAL3 monoclonal antibodyHuman
GM-Tg-rg-MP0813-Ab-1/ GM-Tg-rg-MP0813-Ab-2Anti-Rat MICAL3 monoclonal antibodyRat
GM-Tg-mg-MP0813-Ab-1/ GM-Tg-mg-MP0813-Ab-2Anti-Mouse MICAL3 monoclonal antibodyMouse
GM-Tg-cynog-MP0813-Ab-1/ GM-Tg-cynog-MP0813-Ab-2Anti-Cynomolgus/ Rhesus macaque MICAL3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0813-Ab-1/ GM-Tg-felg-MP0813-Ab-2Anti-Feline MICAL3 monoclonal antibodyFeline
GM-Tg-cang-MP0813-Ab-1/ GM-Tg-cang-MP0813-Ab-2Anti-Canine MICAL3 monoclonal antibodyCanine
GM-Tg-bovg-MP0813-Ab-1/ GM-Tg-bovg-MP0813-Ab-2Anti-Bovine MICAL3 monoclonal antibodyBovine
GM-Tg-equg-MP0813-Ab-1/ GM-Tg-equg-MP0813-Ab-2Anti-Equine MICAL3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0813-Ab-1/ GM-Tg-hg-MP0813-Ab-2; GM-Tg-rg-MP0813-Ab-1/ GM-Tg-rg-MP0813-Ab-2;
GM-Tg-mg-MP0813-Ab-1/ GM-Tg-mg-MP0813-Ab-2; GM-Tg-cynog-MP0813-Ab-1/ GM-Tg-cynog-MP0813-Ab-2;
GM-Tg-felg-MP0813-Ab-1/ GM-Tg-felg-MP0813-Ab-2; GM-Tg-cang-MP0813-Ab-1/ GM-Tg-cang-MP0813-Ab-2;
GM-Tg-bovg-MP0813-Ab-1/ GM-Tg-bovg-MP0813-Ab-2; GM-Tg-equg-MP0813-Ab-1/ GM-Tg-equg-MP0813-Ab-2
Products NameAnti-MICAL3 monoclonal antibody
Formatmab
Target NameMICAL3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MICAL3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MICA3/ MICAL3/ MICAL-3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0813
    Target NameMICAL3
    Gene ID57553,194401,362427,710292,486761,101081558,532244,100054807
    Gene Symbol and SynonymsC130040D16Rik,MICAL-3,MICAL3,mKIAA1364
    Uniprot AccessionQ7RTP6,G3MWR8
    Uniprot Entry NameMICA3_HUMAN,MICA3_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000243156
    Target ClassificationN/A

    The target: MICAL3, gene name: MICAL3, also named as MICAL-3. Enables actin binding activity. Involved in actin filament depolymerization. Located in several cellular components, including Flemming body; intercellular bridge; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.