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Anti-MIP/ AQP0/ CTRCT15 monoclonal antibody
Anti-MIP/ AQP0/ CTRCT15 antibody for FACS & in-vivo assay
Go to MIP/MIP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0815-Ab-1/ GM-Tg-hg-MP0815-Ab-2 | Anti-Human MIP monoclonal antibody | Human |
| GM-Tg-rg-MP0815-Ab-1/ GM-Tg-rg-MP0815-Ab-2 | Anti-Rat MIP monoclonal antibody | Rat |
| GM-Tg-mg-MP0815-Ab-1/ GM-Tg-mg-MP0815-Ab-2 | Anti-Mouse MIP monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0815-Ab-1/ GM-Tg-cynog-MP0815-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MIP monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0815-Ab-1/ GM-Tg-felg-MP0815-Ab-2 | Anti-Feline MIP monoclonal antibody | Feline |
| GM-Tg-cang-MP0815-Ab-1/ GM-Tg-cang-MP0815-Ab-2 | Anti-Canine MIP monoclonal antibody | Canine |
| GM-Tg-bovg-MP0815-Ab-1/ GM-Tg-bovg-MP0815-Ab-2 | Anti-Bovine MIP monoclonal antibody | Bovine |
| GM-Tg-equg-MP0815-Ab-1/ GM-Tg-equg-MP0815-Ab-2 | Anti-Equine MIP monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0815-Ab-1/ GM-Tg-hg-MP0815-Ab-2; GM-Tg-rg-MP0815-Ab-1/ GM-Tg-rg-MP0815-Ab-2; GM-Tg-mg-MP0815-Ab-1/ GM-Tg-mg-MP0815-Ab-2; GM-Tg-cynog-MP0815-Ab-1/ GM-Tg-cynog-MP0815-Ab-2; GM-Tg-felg-MP0815-Ab-1/ GM-Tg-felg-MP0815-Ab-2; GM-Tg-cang-MP0815-Ab-1/ GM-Tg-cang-MP0815-Ab-2; GM-Tg-bovg-MP0815-Ab-1/ GM-Tg-bovg-MP0815-Ab-2; GM-Tg-equg-MP0815-Ab-1/ GM-Tg-equg-MP0815-Ab-2 |
| Products Name | Anti-MIP monoclonal antibody |
| Format | mab |
| Target Name | MIP |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MIP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species MIP/ AQP0/ CTRCT15 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP000258 | human MIP Lentivirus plasmid |
| ORF Viral Vector | vGMLP000258 | human MIP Lentivirus particle |
| ORF Viral Vector | pGMLPm004525 | mouse Mip Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004525 | mouse Mip Lentivirus particle |
Target information
| Target ID | GM-MP0815 |
| Target Name | MIP |
| Gene ID | 4284,17339,25480,712901,607104,101099733,280859,100052571 |
| Gene Symbol and Synonyms | AQP0,Cat,CTRCT15,Cts,Hfi,LIM1,Lop,MIP,MIP26,MP22,MP26,shrivelled,Svl |
| Uniprot Accession | P30301,P09011,A2IBY8,P06624 |
| Uniprot Entry Name | MIP_HUMAN,MIP_RAT,MIP_CANLF,MIP_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000135517 |
| Target Classification | N/A |
The target: MIP, gene name: MIP, also named as AQP0, CTRCT15, LIM126, MP26, MIP. Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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