Anti-MPDZ/ HYC2/ MUPP1 monoclonal antibody

Anti-MPDZ/ HYC2/ MUPP1 antibody for FACS & in-vivo assay

Target products collectionGo to MPDZ/MPDZ products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0822-Ab-1/ GM-Tg-hg-MP0822-Ab-2Anti-Human MPDZ monoclonal antibodyHuman
GM-Tg-rg-MP0822-Ab-1/ GM-Tg-rg-MP0822-Ab-2Anti-Rat MPDZ monoclonal antibodyRat
GM-Tg-mg-MP0822-Ab-1/ GM-Tg-mg-MP0822-Ab-2Anti-Mouse MPDZ monoclonal antibodyMouse
GM-Tg-cynog-MP0822-Ab-1/ GM-Tg-cynog-MP0822-Ab-2Anti-Cynomolgus/ Rhesus macaque MPDZ monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0822-Ab-1/ GM-Tg-felg-MP0822-Ab-2Anti-Feline MPDZ monoclonal antibodyFeline
GM-Tg-cang-MP0822-Ab-1/ GM-Tg-cang-MP0822-Ab-2Anti-Canine MPDZ monoclonal antibodyCanine
GM-Tg-bovg-MP0822-Ab-1/ GM-Tg-bovg-MP0822-Ab-2Anti-Bovine MPDZ monoclonal antibodyBovine
GM-Tg-equg-MP0822-Ab-1/ GM-Tg-equg-MP0822-Ab-2Anti-Equine MPDZ monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0822-Ab-1/ GM-Tg-hg-MP0822-Ab-2; GM-Tg-rg-MP0822-Ab-1/ GM-Tg-rg-MP0822-Ab-2;
GM-Tg-mg-MP0822-Ab-1/ GM-Tg-mg-MP0822-Ab-2; GM-Tg-cynog-MP0822-Ab-1/ GM-Tg-cynog-MP0822-Ab-2;
GM-Tg-felg-MP0822-Ab-1/ GM-Tg-felg-MP0822-Ab-2; GM-Tg-cang-MP0822-Ab-1/ GM-Tg-cang-MP0822-Ab-2;
GM-Tg-bovg-MP0822-Ab-1/ GM-Tg-bovg-MP0822-Ab-2; GM-Tg-equg-MP0822-Ab-1/ GM-Tg-equg-MP0822-Ab-2
Products NameAnti-MPDZ monoclonal antibody
Formatmab
Target NameMPDZ
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MPDZ benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MPDZ/ HYC2/ MUPP1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0822
    Target NameMPDZ
    Gene ID8777,17475,29365,715817,474708,101095690,536863,100052067
    Gene Symbol and SynonymsB930003D11Rik,HYC2,MPDZ,MUPP1
    Uniprot AccessionO75970,O55164
    Uniprot Entry NameMPDZ_HUMAN,MPDZ_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000107186
    Target ClassificationN/A

    The target: MPDZ, gene name: MPDZ, also named as HYC2, MUPP1. The protein encoded by this gene has multiple PDZ domains, which are hallmarks of protein-protein interactions. The encoded protein is known to interact with the HTR2C receptor and may cause it to clump at the cell surface. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.