Anti-MRGRE/ MRGPRE/ GPR167 monoclonal antibody

Anti-MRGRE/ MRGPRE/ GPR167 antibody for FACS & in-vivo assay

Target products collectionGo to MRGPRE/MRGPRE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0831-Ab-1/ GM-Tg-hg-MP0831-Ab-2Anti-Human MRGPRE monoclonal antibodyHuman
GM-Tg-rg-MP0831-Ab-1/ GM-Tg-rg-MP0831-Ab-2Anti-Rat MRGPRE monoclonal antibodyRat
GM-Tg-mg-MP0831-Ab-1/ GM-Tg-mg-MP0831-Ab-2Anti-Mouse MRGPRE monoclonal antibodyMouse
GM-Tg-cynog-MP0831-Ab-1/ GM-Tg-cynog-MP0831-Ab-2Anti-Cynomolgus/ Rhesus macaque MRGPRE monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0831-Ab-1/ GM-Tg-felg-MP0831-Ab-2Anti-Feline MRGPRE monoclonal antibodyFeline
GM-Tg-cang-MP0831-Ab-1/ GM-Tg-cang-MP0831-Ab-2Anti-Canine MRGPRE monoclonal antibodyCanine
GM-Tg-bovg-MP0831-Ab-1/ GM-Tg-bovg-MP0831-Ab-2Anti-Bovine MRGPRE monoclonal antibodyBovine
GM-Tg-equg-MP0831-Ab-1/ GM-Tg-equg-MP0831-Ab-2Anti-Equine MRGPRE monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0831-Ab-1/ GM-Tg-hg-MP0831-Ab-2; GM-Tg-rg-MP0831-Ab-1/ GM-Tg-rg-MP0831-Ab-2;
GM-Tg-mg-MP0831-Ab-1/ GM-Tg-mg-MP0831-Ab-2; GM-Tg-cynog-MP0831-Ab-1/ GM-Tg-cynog-MP0831-Ab-2;
GM-Tg-felg-MP0831-Ab-1/ GM-Tg-felg-MP0831-Ab-2; GM-Tg-cang-MP0831-Ab-1/ GM-Tg-cang-MP0831-Ab-2;
GM-Tg-bovg-MP0831-Ab-1/ GM-Tg-bovg-MP0831-Ab-2; GM-Tg-equg-MP0831-Ab-1/ GM-Tg-equg-MP0831-Ab-2
Products NameAnti-MRGPRE monoclonal antibody
Formatmab
Target NameMRGPRE
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MRGPRE benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MRGRE/ MRGPRE/ GPR167 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0831
    Target NameMRGPRE
    Gene ID116534,244238,404660,706822,123380252
    Gene Symbol and SynonymsC130069N09Rik,Ebrt3,GPR167,MGRF,MRGE,MRGPRE
    Uniprot AccessionQ86SM8,Q7TN40
    Uniprot Entry NameMRGRE_HUMAN,MRGRE_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000184350
    Target ClassificationGPCR

    The target: MRGPRE, gene name: MRGPRE, also named as GPR167, MGRF, MRGE. Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.