Anti-MRGRG/ MRGPRG/ GPR169 monoclonal antibody

Anti-MRGRG/ MRGPRG/ GPR169 antibody for FACS & in-vivo assay

Target products collectionGo to MRGPRG/MRGPRG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0833-Ab-1/ GM-Tg-hg-MP0833-Ab-2Anti-Human MRGPRG monoclonal antibodyHuman
GM-Tg-rg-MP0833-Ab-1/ GM-Tg-rg-MP0833-Ab-2Anti-Rat MRGPRG monoclonal antibodyRat
GM-Tg-mg-MP0833-Ab-1/ GM-Tg-mg-MP0833-Ab-2Anti-Mouse MRGPRG monoclonal antibodyMouse
GM-Tg-cynog-MP0833-Ab-1/ GM-Tg-cynog-MP0833-Ab-2Anti-Cynomolgus/ Rhesus macaque MRGPRG monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0833-Ab-1/ GM-Tg-felg-MP0833-Ab-2Anti-Feline MRGPRG monoclonal antibodyFeline
GM-Tg-cang-MP0833-Ab-1/ GM-Tg-cang-MP0833-Ab-2Anti-Canine MRGPRG monoclonal antibodyCanine
GM-Tg-bovg-MP0833-Ab-1/ GM-Tg-bovg-MP0833-Ab-2Anti-Bovine MRGPRG monoclonal antibodyBovine
GM-Tg-equg-MP0833-Ab-1/ GM-Tg-equg-MP0833-Ab-2Anti-Equine MRGPRG monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0833-Ab-1/ GM-Tg-hg-MP0833-Ab-2; GM-Tg-rg-MP0833-Ab-1/ GM-Tg-rg-MP0833-Ab-2;
GM-Tg-mg-MP0833-Ab-1/ GM-Tg-mg-MP0833-Ab-2; GM-Tg-cynog-MP0833-Ab-1/ GM-Tg-cynog-MP0833-Ab-2;
GM-Tg-felg-MP0833-Ab-1/ GM-Tg-felg-MP0833-Ab-2; GM-Tg-cang-MP0833-Ab-1/ GM-Tg-cang-MP0833-Ab-2;
GM-Tg-bovg-MP0833-Ab-1/ GM-Tg-bovg-MP0833-Ab-2; GM-Tg-equg-MP0833-Ab-1/ GM-Tg-equg-MP0833-Ab-2
Products NameAnti-MRGPRG monoclonal antibody
Formatmab
Target NameMRGPRG
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MRGPRG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MRGRG/ MRGPRG/ GPR169 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0833
    Target NameMRGPRG
    Gene ID386746,381974,309133,721253,483672,101091899,618771,102150910
    Gene Symbol and SynonymsGm1098,GPR169,MGRE,MRGG,MRGPRG
    Uniprot AccessionQ86SM5,Q7TN39
    Uniprot Entry NameMRGRG_HUMAN,MRGRG_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000182170
    Target ClassificationGPCR

    The target: MRGPRG, gene name: MRGPRG, also named as GPR169, MRGG. Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.