Anti-MRGX4/ MRGPRX4/ GPCR monoclonal antibody

Anti-MRGX4/ MRGPRX4/ GPCR antibody for FACS & in-vivo assay

Target products collectionGo to MRGPRX4/MRGPRX4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0835-Ab-1/ GM-Tg-hg-MP0835-Ab-2Anti-Human MRGPRX4 monoclonal antibodyHuman
GM-Tg-rg-MP0835-Ab-1/ GM-Tg-rg-MP0835-Ab-2Anti-Rat MRGPRX4 monoclonal antibodyRat
GM-Tg-mg-MP0835-Ab-1/ GM-Tg-mg-MP0835-Ab-2Anti-Mouse MRGPRX4 monoclonal antibodyMouse
GM-Tg-cynog-MP0835-Ab-1/ GM-Tg-cynog-MP0835-Ab-2Anti-Cynomolgus/ Rhesus macaque MRGPRX4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0835-Ab-1/ GM-Tg-felg-MP0835-Ab-2Anti-Feline MRGPRX4 monoclonal antibodyFeline
GM-Tg-cang-MP0835-Ab-1/ GM-Tg-cang-MP0835-Ab-2Anti-Canine MRGPRX4 monoclonal antibodyCanine
GM-Tg-bovg-MP0835-Ab-1/ GM-Tg-bovg-MP0835-Ab-2Anti-Bovine MRGPRX4 monoclonal antibodyBovine
GM-Tg-equg-MP0835-Ab-1/ GM-Tg-equg-MP0835-Ab-2Anti-Equine MRGPRX4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0835-Ab-1/ GM-Tg-hg-MP0835-Ab-2; GM-Tg-rg-MP0835-Ab-1/ GM-Tg-rg-MP0835-Ab-2;
GM-Tg-mg-MP0835-Ab-1/ GM-Tg-mg-MP0835-Ab-2; GM-Tg-cynog-MP0835-Ab-1/ GM-Tg-cynog-MP0835-Ab-2;
GM-Tg-felg-MP0835-Ab-1/ GM-Tg-felg-MP0835-Ab-2; GM-Tg-cang-MP0835-Ab-1/ GM-Tg-cang-MP0835-Ab-2;
GM-Tg-bovg-MP0835-Ab-1/ GM-Tg-bovg-MP0835-Ab-2; GM-Tg-equg-MP0835-Ab-1/ GM-Tg-equg-MP0835-Ab-2
Products NameAnti-MRGPRX4 monoclonal antibody
Formatmab
Target NameMRGPRX4
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MRGPRX4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MRGX4/ MRGPRX4/ GPCR VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP005035human MRGPRX4 Lentivirus plasmid
    ORF Viral VectorvGMLP005035human MRGPRX4 Lentivirus particle


    Target information

    Target IDGM-MP0835
    Target NameMRGPRX4
    Gene ID117196
    Gene Symbol and SynonymsGPCR,MRGPRX4,MRGX4,SNSR6
    Uniprot AccessionQ96LA9
    Uniprot Entry NameMRGX4_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000179817
    Target ClassificationGPCR

    The target: MRGPRX4, gene name: MRGPRX4, also named as GPCR, MRGX4, SNSR6. Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within chemosensory behavior and hematopoietic progenitor cell differentiation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.