Anti-M4A4A/ MS4A4A/ 4SPAN1 monoclonal antibody

Anti-M4A4A/ MS4A4A/ 4SPAN1 antibody for FACS & in-vivo assay

Target products collectionGo to MS4A4A/MS4A4A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0844-Ab-1/ GM-Tg-hg-MP0844-Ab-2Anti-Human MS4A4A monoclonal antibodyHuman
GM-Tg-rg-MP0844-Ab-1/ GM-Tg-rg-MP0844-Ab-2Anti-Rat MS4A4A monoclonal antibodyRat
GM-Tg-mg-MP0844-Ab-1/ GM-Tg-mg-MP0844-Ab-2Anti-Mouse MS4A4A monoclonal antibodyMouse
GM-Tg-cynog-MP0844-Ab-1/ GM-Tg-cynog-MP0844-Ab-2Anti-Cynomolgus/ Rhesus macaque MS4A4A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0844-Ab-1/ GM-Tg-felg-MP0844-Ab-2Anti-Feline MS4A4A monoclonal antibodyFeline
GM-Tg-cang-MP0844-Ab-1/ GM-Tg-cang-MP0844-Ab-2Anti-Canine MS4A4A monoclonal antibodyCanine
GM-Tg-bovg-MP0844-Ab-1/ GM-Tg-bovg-MP0844-Ab-2Anti-Bovine MS4A4A monoclonal antibodyBovine
GM-Tg-equg-MP0844-Ab-1/ GM-Tg-equg-MP0844-Ab-2Anti-Equine MS4A4A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0844-Ab-1/ GM-Tg-hg-MP0844-Ab-2; GM-Tg-rg-MP0844-Ab-1/ GM-Tg-rg-MP0844-Ab-2;
GM-Tg-mg-MP0844-Ab-1/ GM-Tg-mg-MP0844-Ab-2; GM-Tg-cynog-MP0844-Ab-1/ GM-Tg-cynog-MP0844-Ab-2;
GM-Tg-felg-MP0844-Ab-1/ GM-Tg-felg-MP0844-Ab-2; GM-Tg-cang-MP0844-Ab-1/ GM-Tg-cang-MP0844-Ab-2;
GM-Tg-bovg-MP0844-Ab-1/ GM-Tg-bovg-MP0844-Ab-2; GM-Tg-equg-MP0844-Ab-1/ GM-Tg-equg-MP0844-Ab-2
Products NameAnti-MS4A4A monoclonal antibody
Formatmab
Target NameMS4A4A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MS4A4A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species M4A4A/ MS4A4A/ 4SPAN1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0844
    Target NameMS4A4A
    Gene ID51338,666907,698027
    Gene Symbol and Synonyms4SPAN1,CD20-L1,CD20L1,EG666907,HDCME31P,MS4A4,MS4A4A,MS4A7
    Uniprot AccessionQ96JQ5
    Uniprot Entry NameM4A4A_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000110079
    Target ClassificationN/A

    The target: MS4A4A, gene name: MS4A4A, also named as 4SPAN1, CD20-L1, CD20L1, HDCME31P, MS4A4, MS4A7. This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features, similar intron/exon splice boundaries, and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.