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Anti-MS4A7/ 4SPAN2/ CD20L4 monoclonal antibody
Anti-MS4A7/ 4SPAN2/ CD20L4 antibody for FACS & in-vivo assay
Go to MS4A7/MS4A7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0849-Ab-1/ GM-Tg-hg-MP0849-Ab-2 | Anti-Human MS4A7 monoclonal antibody | Human |
| GM-Tg-rg-MP0849-Ab-1/ GM-Tg-rg-MP0849-Ab-2 | Anti-Rat MS4A7 monoclonal antibody | Rat |
| GM-Tg-mg-MP0849-Ab-1/ GM-Tg-mg-MP0849-Ab-2 | Anti-Mouse MS4A7 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0849-Ab-1/ GM-Tg-cynog-MP0849-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MS4A7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0849-Ab-1/ GM-Tg-felg-MP0849-Ab-2 | Anti-Feline MS4A7 monoclonal antibody | Feline |
| GM-Tg-cang-MP0849-Ab-1/ GM-Tg-cang-MP0849-Ab-2 | Anti-Canine MS4A7 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0849-Ab-1/ GM-Tg-bovg-MP0849-Ab-2 | Anti-Bovine MS4A7 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0849-Ab-1/ GM-Tg-equg-MP0849-Ab-2 | Anti-Equine MS4A7 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0849-Ab-1/ GM-Tg-hg-MP0849-Ab-2; GM-Tg-rg-MP0849-Ab-1/ GM-Tg-rg-MP0849-Ab-2; GM-Tg-mg-MP0849-Ab-1/ GM-Tg-mg-MP0849-Ab-2; GM-Tg-cynog-MP0849-Ab-1/ GM-Tg-cynog-MP0849-Ab-2; GM-Tg-felg-MP0849-Ab-1/ GM-Tg-felg-MP0849-Ab-2; GM-Tg-cang-MP0849-Ab-1/ GM-Tg-cang-MP0849-Ab-2; GM-Tg-bovg-MP0849-Ab-1/ GM-Tg-bovg-MP0849-Ab-2; GM-Tg-equg-MP0849-Ab-1/ GM-Tg-equg-MP0849-Ab-2 |
| Products Name | Anti-MS4A7 monoclonal antibody |
| Format | mab |
| Target Name | MS4A7 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MS4A7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species MS4A7/ 4SPAN2/ CD20L4 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP0849 |
| Target Name | MS4A7 |
| Gene ID | 58475,109225,293744,697200,612564,101100917,100061443 |
| Gene Symbol and Synonyms | 4SPAN2,9130422I10Rik,A430103C15Rik,CD20L4,CFFM4,CFFMA,MS4A7,MS4A8 |
| Uniprot Accession | Q9GZW8 |
| Uniprot Entry Name | MS4A7_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000166927 |
| Target Classification | N/A |
The target: MS4A7, gene name: MS4A7, also named as 4SPAN2, CD20L4, CFFM4, MS4A8. This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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