Anti-MUC3A/ MUC-3A/ MUC3 monoclonal antibody

Anti-MUC3A/ MUC-3A/ MUC3 antibody for FACS & in-vivo assay

Target products collectionGo to MUC3A/MUC3A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0856-Ab-1/ GM-Tg-hg-MP0856-Ab-2Anti-Human MUC3A monoclonal antibodyHuman
GM-Tg-rg-MP0856-Ab-1/ GM-Tg-rg-MP0856-Ab-2Anti-Rat MUC3A monoclonal antibodyRat
GM-Tg-mg-MP0856-Ab-1/ GM-Tg-mg-MP0856-Ab-2Anti-Mouse MUC3A monoclonal antibodyMouse
GM-Tg-cynog-MP0856-Ab-1/ GM-Tg-cynog-MP0856-Ab-2Anti-Cynomolgus/ Rhesus macaque MUC3A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0856-Ab-1/ GM-Tg-felg-MP0856-Ab-2Anti-Feline MUC3A monoclonal antibodyFeline
GM-Tg-cang-MP0856-Ab-1/ GM-Tg-cang-MP0856-Ab-2Anti-Canine MUC3A monoclonal antibodyCanine
GM-Tg-bovg-MP0856-Ab-1/ GM-Tg-bovg-MP0856-Ab-2Anti-Bovine MUC3A monoclonal antibodyBovine
GM-Tg-equg-MP0856-Ab-1/ GM-Tg-equg-MP0856-Ab-2Anti-Equine MUC3A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0856-Ab-1/ GM-Tg-hg-MP0856-Ab-2; GM-Tg-rg-MP0856-Ab-1/ GM-Tg-rg-MP0856-Ab-2;
GM-Tg-mg-MP0856-Ab-1/ GM-Tg-mg-MP0856-Ab-2; GM-Tg-cynog-MP0856-Ab-1/ GM-Tg-cynog-MP0856-Ab-2;
GM-Tg-felg-MP0856-Ab-1/ GM-Tg-felg-MP0856-Ab-2; GM-Tg-cang-MP0856-Ab-1/ GM-Tg-cang-MP0856-Ab-2;
GM-Tg-bovg-MP0856-Ab-1/ GM-Tg-bovg-MP0856-Ab-2; GM-Tg-equg-MP0856-Ab-1/ GM-Tg-equg-MP0856-Ab-2
Products NameAnti-MUC3A monoclonal antibody
Formatmab
Target NameMUC3A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MUC3A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MUC3A/ MUC-3A/ MUC3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0856
    Target NameMUC3A
    Gene ID4584,619309,123382584,112444312
    Gene Symbol and SynonymsA630081J09Rik,MUC-3A,MUC3,MUC3A
    Uniprot AccessionQ02505
    Uniprot Entry NameMUC3A_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169894
    Target ClassificationN/A

    The target: MUC3A, gene name: MUC3A, also named as MUC-3A, MUC3. The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Each of the genes contains at least one large domain of tandemly repeated sequence that encodes the peptide sequence rich in serine and/or threonine residues, which carries most of the O-linked glycosylation (Gendler and Spicer, 1995 [PubMed 7778880]).[supplied by OMIM, Aug 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.