Anti-NKAI2/ NKAIN2/ FAM77B monoclonal antibody

Anti-NKAI2/ NKAIN2/ FAM77B antibody for FACS & in-vivo assay

Target products collectionGo to NKAIN2/NKAIN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0881-Ab-1/ GM-Tg-hg-MP0881-Ab-2Anti-Human NKAIN2 monoclonal antibodyHuman
GM-Tg-rg-MP0881-Ab-1/ GM-Tg-rg-MP0881-Ab-2Anti-Rat NKAIN2 monoclonal antibodyRat
GM-Tg-mg-MP0881-Ab-1/ GM-Tg-mg-MP0881-Ab-2Anti-Mouse NKAIN2 monoclonal antibodyMouse
GM-Tg-cynog-MP0881-Ab-1/ GM-Tg-cynog-MP0881-Ab-2Anti-Cynomolgus/ Rhesus macaque NKAIN2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0881-Ab-1/ GM-Tg-felg-MP0881-Ab-2Anti-Feline NKAIN2 monoclonal antibodyFeline
GM-Tg-cang-MP0881-Ab-1/ GM-Tg-cang-MP0881-Ab-2Anti-Canine NKAIN2 monoclonal antibodyCanine
GM-Tg-bovg-MP0881-Ab-1/ GM-Tg-bovg-MP0881-Ab-2Anti-Bovine NKAIN2 monoclonal antibodyBovine
GM-Tg-equg-MP0881-Ab-1/ GM-Tg-equg-MP0881-Ab-2Anti-Equine NKAIN2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0881-Ab-1/ GM-Tg-hg-MP0881-Ab-2; GM-Tg-rg-MP0881-Ab-1/ GM-Tg-rg-MP0881-Ab-2;
GM-Tg-mg-MP0881-Ab-1/ GM-Tg-mg-MP0881-Ab-2; GM-Tg-cynog-MP0881-Ab-1/ GM-Tg-cynog-MP0881-Ab-2;
GM-Tg-felg-MP0881-Ab-1/ GM-Tg-felg-MP0881-Ab-2; GM-Tg-cang-MP0881-Ab-1/ GM-Tg-cang-MP0881-Ab-2;
GM-Tg-bovg-MP0881-Ab-1/ GM-Tg-bovg-MP0881-Ab-2; GM-Tg-equg-MP0881-Ab-1/ GM-Tg-equg-MP0881-Ab-2
Products NameAnti-NKAIN2 monoclonal antibody
Formatmab
Target NameNKAIN2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NKAIN2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NKAI2/ NKAIN2/ FAM77B VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0881
    Target NameNKAIN2
    Gene ID154215,432450,102551716,713237,100688012,101081049,787444,100067309
    Gene Symbol and Synonyms6330571D19Rik,FAM77B,NKAIN2,NKAIP2,TCBA,TCBA1
    Uniprot AccessionQ5VXU1,A6QNL6
    Uniprot Entry NameNKAI2_HUMAN,NKAI2_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000188580
    Target ClassificationN/A

    The target: NKAIN2, gene name: NKAIN2, also named as FAM77B, NKAIP2, TCBA, TCBA1. This gene encodes a transmembrane protein that interacts with the beta subunit of a sodium/potassium-transporting ATPase. A chromosomal translocation involving this gene is a cause of lymphoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.