Anti-NLGNY/ NLGN4Y/ HNL4Y monoclonal antibody

Anti-NLGNY/ NLGN4Y/ HNL4Y antibody for FACS & in-vivo assay

Target products collectionGo to NLGN4Y/NLGN4Y products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0890-Ab-1/ GM-Tg-hg-MP0890-Ab-2Anti-Human NLGN4Y monoclonal antibodyHuman
GM-Tg-rg-MP0890-Ab-1/ GM-Tg-rg-MP0890-Ab-2Anti-Rat NLGN4Y monoclonal antibodyRat
GM-Tg-mg-MP0890-Ab-1/ GM-Tg-mg-MP0890-Ab-2Anti-Mouse NLGN4Y monoclonal antibodyMouse
GM-Tg-cynog-MP0890-Ab-1/ GM-Tg-cynog-MP0890-Ab-2Anti-Cynomolgus/ Rhesus macaque NLGN4Y monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0890-Ab-1/ GM-Tg-felg-MP0890-Ab-2Anti-Feline NLGN4Y monoclonal antibodyFeline
GM-Tg-cang-MP0890-Ab-1/ GM-Tg-cang-MP0890-Ab-2Anti-Canine NLGN4Y monoclonal antibodyCanine
GM-Tg-bovg-MP0890-Ab-1/ GM-Tg-bovg-MP0890-Ab-2Anti-Bovine NLGN4Y monoclonal antibodyBovine
GM-Tg-equg-MP0890-Ab-1/ GM-Tg-equg-MP0890-Ab-2Anti-Equine NLGN4Y monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0890-Ab-1/ GM-Tg-hg-MP0890-Ab-2; GM-Tg-rg-MP0890-Ab-1/ GM-Tg-rg-MP0890-Ab-2;
GM-Tg-mg-MP0890-Ab-1/ GM-Tg-mg-MP0890-Ab-2; GM-Tg-cynog-MP0890-Ab-1/ GM-Tg-cynog-MP0890-Ab-2;
GM-Tg-felg-MP0890-Ab-1/ GM-Tg-felg-MP0890-Ab-2; GM-Tg-cang-MP0890-Ab-1/ GM-Tg-cang-MP0890-Ab-2;
GM-Tg-bovg-MP0890-Ab-1/ GM-Tg-bovg-MP0890-Ab-2; GM-Tg-equg-MP0890-Ab-1/ GM-Tg-equg-MP0890-Ab-2
Products NameAnti-NLGN4Y monoclonal antibody
Formatmab
Target NameNLGN4Y
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NLGN4Y benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NLGNY/ NLGN4Y/ HNL4Y VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0890
    Target NameNLGN4Y
    Gene ID22829
    Gene Symbol and SynonymsHNL4Y,NLGN4Y
    Uniprot AccessionQ8NFZ3
    Uniprot Entry NameNLGNY_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000165246
    Target ClassificationN/A

    The target: NLGN4Y, gene name: NLGN4Y, also named as HNL4Y. This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Mar 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.