- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-NOX3/ GP91-3/ MOX-2 monoclonal antibody
Anti-NOX3/ GP91-3/ MOX-2 antibody for FACS & in-vivo assay
Go to NOX3/NOX3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0892-Ab-1/ GM-Tg-hg-MP0892-Ab-2 | Anti-Human NOX3 monoclonal antibody | Human |
| GM-Tg-rg-MP0892-Ab-1/ GM-Tg-rg-MP0892-Ab-2 | Anti-Rat NOX3 monoclonal antibody | Rat |
| GM-Tg-mg-MP0892-Ab-1/ GM-Tg-mg-MP0892-Ab-2 | Anti-Mouse NOX3 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0892-Ab-1/ GM-Tg-cynog-MP0892-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NOX3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0892-Ab-1/ GM-Tg-felg-MP0892-Ab-2 | Anti-Feline NOX3 monoclonal antibody | Feline |
| GM-Tg-cang-MP0892-Ab-1/ GM-Tg-cang-MP0892-Ab-2 | Anti-Canine NOX3 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0892-Ab-1/ GM-Tg-bovg-MP0892-Ab-2 | Anti-Bovine NOX3 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0892-Ab-1/ GM-Tg-equg-MP0892-Ab-2 | Anti-Equine NOX3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0892-Ab-1/ GM-Tg-hg-MP0892-Ab-2; GM-Tg-rg-MP0892-Ab-1/ GM-Tg-rg-MP0892-Ab-2; GM-Tg-mg-MP0892-Ab-1/ GM-Tg-mg-MP0892-Ab-2; GM-Tg-cynog-MP0892-Ab-1/ GM-Tg-cynog-MP0892-Ab-2; GM-Tg-felg-MP0892-Ab-1/ GM-Tg-felg-MP0892-Ab-2; GM-Tg-cang-MP0892-Ab-1/ GM-Tg-cang-MP0892-Ab-2; GM-Tg-bovg-MP0892-Ab-1/ GM-Tg-bovg-MP0892-Ab-2; GM-Tg-equg-MP0892-Ab-1/ GM-Tg-equg-MP0892-Ab-2 |
| Products Name | Anti-NOX3 monoclonal antibody |
| Format | mab |
| Target Name | NOX3 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-NOX3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species NOX3/ GP91-3/ MOX-2 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP0892 |
| Target Name | NOX3 |
| Gene ID | 50508,224480,292279,701576,484046,101090520,526999,100061382 |
| Gene Symbol and Synonyms | GP91-3,het,MOX-2,nmf250,NOX3 |
| Uniprot Accession | Q9HBY0,Q672K1 |
| Uniprot Entry Name | NOX3_HUMAN,NOX3_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000074771 |
| Target Classification | N/A |
The target: NOX3, gene name: NOX3, also named as GP91-3, MOX-2. This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.[provided by RefSeq, May 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
