Anti-NPTN/ GP55/ GP65 monoclonal antibody

Anti-NPTN/ GP55/ GP65 antibody for FACS & in-vivo assay

Target products collectionGo to NPTN/NPTN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0900-Ab-1/ GM-Tg-hg-MP0900-Ab-2Anti-Human NPTN monoclonal antibodyHuman
GM-Tg-rg-MP0900-Ab-1/ GM-Tg-rg-MP0900-Ab-2Anti-Rat NPTN monoclonal antibodyRat
GM-Tg-mg-MP0900-Ab-1/ GM-Tg-mg-MP0900-Ab-2Anti-Mouse NPTN monoclonal antibodyMouse
GM-Tg-cynog-MP0900-Ab-1/ GM-Tg-cynog-MP0900-Ab-2Anti-Cynomolgus/ Rhesus macaque NPTN monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0900-Ab-1/ GM-Tg-felg-MP0900-Ab-2Anti-Feline NPTN monoclonal antibodyFeline
GM-Tg-cang-MP0900-Ab-1/ GM-Tg-cang-MP0900-Ab-2Anti-Canine NPTN monoclonal antibodyCanine
GM-Tg-bovg-MP0900-Ab-1/ GM-Tg-bovg-MP0900-Ab-2Anti-Bovine NPTN monoclonal antibodyBovine
GM-Tg-equg-MP0900-Ab-1/ GM-Tg-equg-MP0900-Ab-2Anti-Equine NPTN monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0900-Ab-1/ GM-Tg-hg-MP0900-Ab-2; GM-Tg-rg-MP0900-Ab-1/ GM-Tg-rg-MP0900-Ab-2;
GM-Tg-mg-MP0900-Ab-1/ GM-Tg-mg-MP0900-Ab-2; GM-Tg-cynog-MP0900-Ab-1/ GM-Tg-cynog-MP0900-Ab-2;
GM-Tg-felg-MP0900-Ab-1/ GM-Tg-felg-MP0900-Ab-2; GM-Tg-cang-MP0900-Ab-1/ GM-Tg-cang-MP0900-Ab-2;
GM-Tg-bovg-MP0900-Ab-1/ GM-Tg-bovg-MP0900-Ab-2; GM-Tg-equg-MP0900-Ab-1/ GM-Tg-equg-MP0900-Ab-2
Products NameAnti-NPTN monoclonal antibody
Formatmab
Target NameNPTN
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NPTN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NPTN/ GP55/ GP65 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0900
    Target NameNPTN
    Gene ID27020,20320,56064,699627,487637,101088167,540039,100052106
    Gene Symbol and SynonymsGP55,GP65,np55,np65,NPTN,SDFR1,SDR-1,SDR1
    Uniprot AccessionQ9Y639,P97546
    Uniprot Entry NameNPTN_HUMAN,NPTN_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000156642
    Target ClassificationN/A

    The target: NPTN, gene name: NPTN, also named as GP55, GP65, SDFR1, SDR1, np55, np65. This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.