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Anti-NRCAM monoclonal antibody
Anti-NRCAM antibody for FACS & in-vivo assay
Go to NRCAM/NRCAM products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0903-Ab-1/ GM-Tg-hg-MP0903-Ab-2 | Anti-Human NRCAM monoclonal antibody | Human |
| GM-Tg-rg-MP0903-Ab-1/ GM-Tg-rg-MP0903-Ab-2 | Anti-Rat NRCAM monoclonal antibody | Rat |
| GM-Tg-mg-MP0903-Ab-1/ GM-Tg-mg-MP0903-Ab-2 | Anti-Mouse NRCAM monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0903-Ab-1/ GM-Tg-cynog-MP0903-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NRCAM monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0903-Ab-1/ GM-Tg-felg-MP0903-Ab-2 | Anti-Feline NRCAM monoclonal antibody | Feline |
| GM-Tg-cang-MP0903-Ab-1/ GM-Tg-cang-MP0903-Ab-2 | Anti-Canine NRCAM monoclonal antibody | Canine |
| GM-Tg-bovg-MP0903-Ab-1/ GM-Tg-bovg-MP0903-Ab-2 | Anti-Bovine NRCAM monoclonal antibody | Bovine |
| GM-Tg-equg-MP0903-Ab-1/ GM-Tg-equg-MP0903-Ab-2 | Anti-Equine NRCAM monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0903-Ab-1/ GM-Tg-hg-MP0903-Ab-2; GM-Tg-rg-MP0903-Ab-1/ GM-Tg-rg-MP0903-Ab-2; GM-Tg-mg-MP0903-Ab-1/ GM-Tg-mg-MP0903-Ab-2; GM-Tg-cynog-MP0903-Ab-1/ GM-Tg-cynog-MP0903-Ab-2; GM-Tg-felg-MP0903-Ab-1/ GM-Tg-felg-MP0903-Ab-2; GM-Tg-cang-MP0903-Ab-1/ GM-Tg-cang-MP0903-Ab-2; GM-Tg-bovg-MP0903-Ab-1/ GM-Tg-bovg-MP0903-Ab-2; GM-Tg-equg-MP0903-Ab-1/ GM-Tg-equg-MP0903-Ab-2 |
| Products Name | Anti-NRCAM monoclonal antibody |
| Format | mab |
| Target Name | NRCAM |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-NRCAM benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species NRCAM VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP0903 |
| Target Name | NRCAM |
| Gene ID | 4897,319504,497815,574228,475881,101093257,534500,100050997 |
| Gene Symbol and Synonyms | Bravo,C030017F07Rik,C130076O07Rik,mKIAA0343,NEDNMS,Nr-CAM,NRCAM |
| Uniprot Accession | Q92823,P97686 |
| Uniprot Entry Name | NRCAM_HUMAN,NRCAM_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000091129 |
| Target Classification | N/A |
The target: NRCAM, gene name: NRCAM, also named as . Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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