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Anti-LRC33/ NRROS/ ELLP3030 monoclonal antibody
Anti-LRC33/ NRROS/ ELLP3030 antibody for FACS & in-vivo assay
Go to NRROS/NRROS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0906-Ab-1/ GM-Tg-hg-MP0906-Ab-2 | Anti-Human NRROS monoclonal antibody | Human |
| GM-Tg-rg-MP0906-Ab-1/ GM-Tg-rg-MP0906-Ab-2 | Anti-Rat NRROS monoclonal antibody | Rat |
| GM-Tg-mg-MP0906-Ab-1/ GM-Tg-mg-MP0906-Ab-2 | Anti-Mouse NRROS monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0906-Ab-1/ GM-Tg-cynog-MP0906-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NRROS monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0906-Ab-1/ GM-Tg-felg-MP0906-Ab-2 | Anti-Feline NRROS monoclonal antibody | Feline |
| GM-Tg-cang-MP0906-Ab-1/ GM-Tg-cang-MP0906-Ab-2 | Anti-Canine NRROS monoclonal antibody | Canine |
| GM-Tg-bovg-MP0906-Ab-1/ GM-Tg-bovg-MP0906-Ab-2 | Anti-Bovine NRROS monoclonal antibody | Bovine |
| GM-Tg-equg-MP0906-Ab-1/ GM-Tg-equg-MP0906-Ab-2 | Anti-Equine NRROS monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0906-Ab-1/ GM-Tg-hg-MP0906-Ab-2; GM-Tg-rg-MP0906-Ab-1/ GM-Tg-rg-MP0906-Ab-2; GM-Tg-mg-MP0906-Ab-1/ GM-Tg-mg-MP0906-Ab-2; GM-Tg-cynog-MP0906-Ab-1/ GM-Tg-cynog-MP0906-Ab-2; GM-Tg-felg-MP0906-Ab-1/ GM-Tg-felg-MP0906-Ab-2; GM-Tg-cang-MP0906-Ab-1/ GM-Tg-cang-MP0906-Ab-2; GM-Tg-bovg-MP0906-Ab-1/ GM-Tg-bovg-MP0906-Ab-2; GM-Tg-equg-MP0906-Ab-1/ GM-Tg-equg-MP0906-Ab-2 |
| Products Name | Anti-NRROS monoclonal antibody |
| Format | mab |
| Target Name | NRROS |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-NRROS benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species LRC33/ NRROS/ ELLP3030 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP0906 |
| Target Name | NRROS |
| Gene ID | 375387,224109,303875,710573,488032,101082086,510688,100069731 |
| Gene Symbol and Synonyms | E430025L02Rik,ELLP3030,GARPL1,Lrcc33,LRRC33,NRROS,RGD1310771,SENEBAC,UNQ3030 |
| Uniprot Accession | Q86YC3,Q5BK65,Q3ZBI5 |
| Uniprot Entry Name | LRC33_HUMAN,LRC33_RAT,LRC33_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000174004 |
| Target Classification | N/A |
The target: NRROS, gene name: NRROS, also named as ELLP3030, GARPL1, LRRC33, UNQ3030. Enables transforming growth factor beta binding activity. Predicted to be involved in several processes, including microglia development; sequestering of TGFbeta in extracellular matrix; and transforming growth factor beta1 activation. Located in cell surface. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
