Anti-NTNG1/ Lmnt1 monoclonal antibody

Anti-NTNG1/ Lmnt1 antibody for FACS & in-vivo assay

Target products collectionGo to NTNG1/NTNG1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0913-Ab-1/ GM-Tg-hg-MP0913-Ab-2Anti-Human NTNG1 monoclonal antibodyHuman
GM-Tg-rg-MP0913-Ab-1/ GM-Tg-rg-MP0913-Ab-2Anti-Rat NTNG1 monoclonal antibodyRat
GM-Tg-mg-MP0913-Ab-1/ GM-Tg-mg-MP0913-Ab-2Anti-Mouse NTNG1 monoclonal antibodyMouse
GM-Tg-cynog-MP0913-Ab-1/ GM-Tg-cynog-MP0913-Ab-2Anti-Cynomolgus/ Rhesus macaque NTNG1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0913-Ab-1/ GM-Tg-felg-MP0913-Ab-2Anti-Feline NTNG1 monoclonal antibodyFeline
GM-Tg-cang-MP0913-Ab-1/ GM-Tg-cang-MP0913-Ab-2Anti-Canine NTNG1 monoclonal antibodyCanine
GM-Tg-bovg-MP0913-Ab-1/ GM-Tg-bovg-MP0913-Ab-2Anti-Bovine NTNG1 monoclonal antibodyBovine
GM-Tg-equg-MP0913-Ab-1/ GM-Tg-equg-MP0913-Ab-2Anti-Equine NTNG1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0913-Ab-1/ GM-Tg-hg-MP0913-Ab-2; GM-Tg-rg-MP0913-Ab-1/ GM-Tg-rg-MP0913-Ab-2;
GM-Tg-mg-MP0913-Ab-1/ GM-Tg-mg-MP0913-Ab-2; GM-Tg-cynog-MP0913-Ab-1/ GM-Tg-cynog-MP0913-Ab-2;
GM-Tg-felg-MP0913-Ab-1/ GM-Tg-felg-MP0913-Ab-2; GM-Tg-cang-MP0913-Ab-1/ GM-Tg-cang-MP0913-Ab-2;
GM-Tg-bovg-MP0913-Ab-1/ GM-Tg-bovg-MP0913-Ab-2; GM-Tg-equg-MP0913-Ab-1/ GM-Tg-equg-MP0913-Ab-2
Products NameAnti-NTNG1 monoclonal antibody
Formatmab
Target NameNTNG1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NTNG1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NTNG1/ Lmnt1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0913
    Target NameNTNG1
    Gene ID22854,80883,295382,694410,490132,101094117,787473,100060362
    Gene Symbol and SynonymsA930010C08Rik,Lmnt1,NetG1,NetrinG1,NTNG1,RGD1563465
    Uniprot AccessionQ9Y2I2
    Uniprot Entry NameNTNG1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000162631
    Target ClassificationN/A

    The target: NTNG1, gene name: NTNG1, also named as Lmnt1. This gene encodes a preproprotein that is processed into a secreted protein containing eukaroytic growth factor (EGF)-like domains. This protein acts to guide axon growth during neuronal development. Polymorphisms in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.