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Anti-OPSG/ OPN1MW/ CBBM monoclonal antibody
Anti-OPSG/ OPN1MW/ CBBM antibody for FACS & in-vivo assay
Go to OPN1MW/OPN1MW products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0921-Ab-1/ GM-Tg-hg-MP0921-Ab-2 | Anti-Human OPN1MW monoclonal antibody | Human |
| GM-Tg-rg-MP0921-Ab-1/ GM-Tg-rg-MP0921-Ab-2 | Anti-Rat OPN1MW monoclonal antibody | Rat |
| GM-Tg-mg-MP0921-Ab-1/ GM-Tg-mg-MP0921-Ab-2 | Anti-Mouse OPN1MW monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0921-Ab-1/ GM-Tg-cynog-MP0921-Ab-2 | Anti-Cynomolgus/ Rhesus macaque OPN1MW monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0921-Ab-1/ GM-Tg-felg-MP0921-Ab-2 | Anti-Feline OPN1MW monoclonal antibody | Feline |
| GM-Tg-cang-MP0921-Ab-1/ GM-Tg-cang-MP0921-Ab-2 | Anti-Canine OPN1MW monoclonal antibody | Canine |
| GM-Tg-bovg-MP0921-Ab-1/ GM-Tg-bovg-MP0921-Ab-2 | Anti-Bovine OPN1MW monoclonal antibody | Bovine |
| GM-Tg-equg-MP0921-Ab-1/ GM-Tg-equg-MP0921-Ab-2 | Anti-Equine OPN1MW monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0921-Ab-1/ GM-Tg-hg-MP0921-Ab-2; GM-Tg-rg-MP0921-Ab-1/ GM-Tg-rg-MP0921-Ab-2; GM-Tg-mg-MP0921-Ab-1/ GM-Tg-mg-MP0921-Ab-2; GM-Tg-cynog-MP0921-Ab-1/ GM-Tg-cynog-MP0921-Ab-2; GM-Tg-felg-MP0921-Ab-1/ GM-Tg-felg-MP0921-Ab-2; GM-Tg-cang-MP0921-Ab-1/ GM-Tg-cang-MP0921-Ab-2; GM-Tg-bovg-MP0921-Ab-1/ GM-Tg-bovg-MP0921-Ab-2; GM-Tg-equg-MP0921-Ab-1/ GM-Tg-equg-MP0921-Ab-2 |
| Products Name | Anti-OPN1MW monoclonal antibody |
| Format | mab |
| Target Name | OPN1MW |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-OPN1MW benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species OPSG/ OPN1MW/ CBBM VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLPm004407 | mouse Opn1mw Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004407 | mouse Opn1mw Lentivirus particle |
Target information
| Target ID | GM-MP0921 |
| Target Name | OPN1MW |
| Gene ID | 2652,14539,89810 |
| Gene Symbol and Synonyms | CBBM,CBD,COD5,GCP,GOP,ML-opsin,Opn1lw,OPN1MW,OPN1MW1,RCP,Rsvp |
| Uniprot Accession | P04001,O35476,O18914 |
| Uniprot Entry Name | OPSG_HUMAN,OPSG_RAT,OPSR_CANLF |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000268221 |
| Target Classification | N/A |
The target: OPN1MW, gene name: OPN1MW, also named as CBBM, CBD, COD5, GCP, GOP1, OPN1MW. This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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