Anti-OPSB/ OPN1SW/ BCP monoclonal antibody

Anti-OPSB/ OPN1SW/ BCP antibody for FACS & in-vivo assay

Target products collectionGo to OPN1SW/OPN1SW products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0923-Ab-1/ GM-Tg-hg-MP0923-Ab-2Anti-Human OPN1SW monoclonal antibodyHuman
GM-Tg-rg-MP0923-Ab-1/ GM-Tg-rg-MP0923-Ab-2Anti-Rat OPN1SW monoclonal antibodyRat
GM-Tg-mg-MP0923-Ab-1/ GM-Tg-mg-MP0923-Ab-2Anti-Mouse OPN1SW monoclonal antibodyMouse
GM-Tg-cynog-MP0923-Ab-1/ GM-Tg-cynog-MP0923-Ab-2Anti-Cynomolgus/ Rhesus macaque OPN1SW monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0923-Ab-1/ GM-Tg-felg-MP0923-Ab-2Anti-Feline OPN1SW monoclonal antibodyFeline
GM-Tg-cang-MP0923-Ab-1/ GM-Tg-cang-MP0923-Ab-2Anti-Canine OPN1SW monoclonal antibodyCanine
GM-Tg-bovg-MP0923-Ab-1/ GM-Tg-bovg-MP0923-Ab-2Anti-Bovine OPN1SW monoclonal antibodyBovine
GM-Tg-equg-MP0923-Ab-1/ GM-Tg-equg-MP0923-Ab-2Anti-Equine OPN1SW monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0923-Ab-1/ GM-Tg-hg-MP0923-Ab-2; GM-Tg-rg-MP0923-Ab-1/ GM-Tg-rg-MP0923-Ab-2;
GM-Tg-mg-MP0923-Ab-1/ GM-Tg-mg-MP0923-Ab-2; GM-Tg-cynog-MP0923-Ab-1/ GM-Tg-cynog-MP0923-Ab-2;
GM-Tg-felg-MP0923-Ab-1/ GM-Tg-felg-MP0923-Ab-2; GM-Tg-cang-MP0923-Ab-1/ GM-Tg-cang-MP0923-Ab-2;
GM-Tg-bovg-MP0923-Ab-1/ GM-Tg-bovg-MP0923-Ab-2; GM-Tg-equg-MP0923-Ab-1/ GM-Tg-equg-MP0923-Ab-2
Products NameAnti-OPN1SW monoclonal antibody
Formatmab
Target NameOPN1SW
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-OPN1SW benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species OPSB/ OPN1SW/ BCP VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0923
    Target NameOPN1SW
    Gene ID611,12057,81644,699981,482267,101080701,282294,100071755
    Gene Symbol and SynonymsBCP,BOP,CBT,OPN1SW
    Uniprot AccessionP03999,Q63652,P51490
    Uniprot Entry NameOPSB_HUMAN,OPSB_RAT,OPSB_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000128617
    Target ClassificationN/A

    The target: OPN1SW, gene name: OPN1SW, also named as BCP, BOP, CBT. This gene belongs to the G-protein coupled receptor 1 family, opsin subfamily. It encodes the blue cone pigment gene which is one of three types of cone photoreceptors responsible for normal color vision. Defects in this gene are the cause of tritan color blindness (tritanopia). Affected individuals lack blue and yellow sensory mechanisms while retaining those for red and green. Defective blue vision is characteristic. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.