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Anti-OR8K3/ OR11-181 monoclonal antibody
Anti-OR8K3/ OR11-181 antibody for FACS & in-vivo assay
Go to OR8K3/OR8K3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1290-Ab-1/ GM-Tg-hg-MP1290-Ab-2 | Anti-Human OR8K3 monoclonal antibody | Human |
| GM-Tg-rg-MP1290-Ab-1/ GM-Tg-rg-MP1290-Ab-2 | Anti-Rat OR8K3 monoclonal antibody | Rat |
| GM-Tg-mg-MP1290-Ab-1/ GM-Tg-mg-MP1290-Ab-2 | Anti-Mouse OR8K3 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1290-Ab-1/ GM-Tg-cynog-MP1290-Ab-2 | Anti-Cynomolgus/ Rhesus macaque OR8K3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1290-Ab-1/ GM-Tg-felg-MP1290-Ab-2 | Anti-Feline OR8K3 monoclonal antibody | Feline |
| GM-Tg-cang-MP1290-Ab-1/ GM-Tg-cang-MP1290-Ab-2 | Anti-Canine OR8K3 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1290-Ab-1/ GM-Tg-bovg-MP1290-Ab-2 | Anti-Bovine OR8K3 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1290-Ab-1/ GM-Tg-equg-MP1290-Ab-2 | Anti-Equine OR8K3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1290-Ab-1/ GM-Tg-hg-MP1290-Ab-2; GM-Tg-rg-MP1290-Ab-1/ GM-Tg-rg-MP1290-Ab-2; GM-Tg-mg-MP1290-Ab-1/ GM-Tg-mg-MP1290-Ab-2; GM-Tg-cynog-MP1290-Ab-1/ GM-Tg-cynog-MP1290-Ab-2; GM-Tg-felg-MP1290-Ab-1/ GM-Tg-felg-MP1290-Ab-2; GM-Tg-cang-MP1290-Ab-1/ GM-Tg-cang-MP1290-Ab-2; GM-Tg-bovg-MP1290-Ab-1/ GM-Tg-bovg-MP1290-Ab-2; GM-Tg-equg-MP1290-Ab-1/ GM-Tg-equg-MP1290-Ab-2 |
| Products Name | Anti-OR8K3 monoclonal antibody |
| Format | mab |
| Target Name | OR8K3 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-OR8K3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species OR8K3/ OR11-181 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP1290 |
| Target Name | OR8K3 |
| Gene ID | 219473,706675 |
| Gene Symbol and Synonyms | LOC706675,OR11-181,OR8K3 |
| Uniprot Accession | Q8NH51 |
| Uniprot Entry Name | OR8K3_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000280314 |
| Target Classification | N/A |
The target: OR8K3, gene name: OR8K3, also named as OR11-181. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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