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Anti-PANX1/ MRS1/ PX1 monoclonal antibody
Anti-PANX1/ MRS1/ PX1 antibody for FACS & in-vivo assay
Go to PANX1/PANX1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1312-Ab-1/ GM-Tg-hg-MP1312-Ab-2 | Anti-Human PANX1 monoclonal antibody | Human |
| GM-Tg-rg-MP1312-Ab-1/ GM-Tg-rg-MP1312-Ab-2 | Anti-Rat PANX1 monoclonal antibody | Rat |
| GM-Tg-mg-MP1312-Ab-1/ GM-Tg-mg-MP1312-Ab-2 | Anti-Mouse PANX1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1312-Ab-1/ GM-Tg-cynog-MP1312-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PANX1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1312-Ab-1/ GM-Tg-felg-MP1312-Ab-2 | Anti-Feline PANX1 monoclonal antibody | Feline |
| GM-Tg-cang-MP1312-Ab-1/ GM-Tg-cang-MP1312-Ab-2 | Anti-Canine PANX1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1312-Ab-1/ GM-Tg-bovg-MP1312-Ab-2 | Anti-Bovine PANX1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1312-Ab-1/ GM-Tg-equg-MP1312-Ab-2 | Anti-Equine PANX1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1312-Ab-1/ GM-Tg-hg-MP1312-Ab-2; GM-Tg-rg-MP1312-Ab-1/ GM-Tg-rg-MP1312-Ab-2; GM-Tg-mg-MP1312-Ab-1/ GM-Tg-mg-MP1312-Ab-2; GM-Tg-cynog-MP1312-Ab-1/ GM-Tg-cynog-MP1312-Ab-2; GM-Tg-felg-MP1312-Ab-1/ GM-Tg-felg-MP1312-Ab-2; GM-Tg-cang-MP1312-Ab-1/ GM-Tg-cang-MP1312-Ab-2; GM-Tg-bovg-MP1312-Ab-1/ GM-Tg-bovg-MP1312-Ab-2; GM-Tg-equg-MP1312-Ab-1/ GM-Tg-equg-MP1312-Ab-2 |
| Products Name | Anti-PANX1 monoclonal antibody |
| Format | mab |
| Target Name | PANX1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PANX1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PANX1/ MRS1/ PX1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP001982 | human PANX1 Lentivirus particle |
| ORF Viral Vector | pGMLP001982 | human PANX1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002644 | mouse Panx1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002644 | mouse Panx1 Lentivirus particle |
Target information
| Target ID | GM-MP1312 |
| Target Name | PANX1 |
| Gene ID | 24145,55991,315435,697204,607532,101081664,528169,100058241 |
| Gene Symbol and Synonyms | MRS1,OOMD7,OZEMA7,pannexin-1,PANX1,PX1,UNQ2529 |
| Uniprot Accession | Q96RD7,P60570 |
| Uniprot Entry Name | PANX1_HUMAN,PANX1_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000110218 |
| Target Classification | N/A |
The target: PANX1, gene name: PANX1, also named as MRS1, PX1, UNQ2529. The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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