Anti-PAQR8/ C6orf33/ LMPB1 monoclonal antibody

Anti-PAQR8/ C6orf33/ LMPB1 antibody for FACS & in-vivo assay

Target products collectionGo to PAQR8/PAQR8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1318-Ab-1/ GM-Tg-hg-MP1318-Ab-2Anti-Human PAQR8 monoclonal antibodyHuman
GM-Tg-rg-MP1318-Ab-1/ GM-Tg-rg-MP1318-Ab-2Anti-Rat PAQR8 monoclonal antibodyRat
GM-Tg-mg-MP1318-Ab-1/ GM-Tg-mg-MP1318-Ab-2Anti-Mouse PAQR8 monoclonal antibodyMouse
GM-Tg-cynog-MP1318-Ab-1/ GM-Tg-cynog-MP1318-Ab-2Anti-Cynomolgus/ Rhesus macaque PAQR8 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1318-Ab-1/ GM-Tg-felg-MP1318-Ab-2Anti-Feline PAQR8 monoclonal antibodyFeline
GM-Tg-cang-MP1318-Ab-1/ GM-Tg-cang-MP1318-Ab-2Anti-Canine PAQR8 monoclonal antibodyCanine
GM-Tg-bovg-MP1318-Ab-1/ GM-Tg-bovg-MP1318-Ab-2Anti-Bovine PAQR8 monoclonal antibodyBovine
GM-Tg-equg-MP1318-Ab-1/ GM-Tg-equg-MP1318-Ab-2Anti-Equine PAQR8 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1318-Ab-1/ GM-Tg-hg-MP1318-Ab-2; GM-Tg-rg-MP1318-Ab-1/ GM-Tg-rg-MP1318-Ab-2;
GM-Tg-mg-MP1318-Ab-1/ GM-Tg-mg-MP1318-Ab-2; GM-Tg-cynog-MP1318-Ab-1/ GM-Tg-cynog-MP1318-Ab-2;
GM-Tg-felg-MP1318-Ab-1/ GM-Tg-felg-MP1318-Ab-2; GM-Tg-cang-MP1318-Ab-1/ GM-Tg-cang-MP1318-Ab-2;
GM-Tg-bovg-MP1318-Ab-1/ GM-Tg-bovg-MP1318-Ab-2; GM-Tg-equg-MP1318-Ab-1/ GM-Tg-equg-MP1318-Ab-2
Products NameAnti-PAQR8 monoclonal antibody
Formatmab
Target NamePAQR8
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PAQR8 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PAQR8/ C6orf33/ LMPB1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1318
    Target NamePAQR8
    Gene ID85315,74229,316275,708418,100855760,109499700,531018,100056251
    Gene Symbol and Synonyms1700019B16Rik,3110001D06Rik,C6orf33,LMPB1,MPRB,PAQR8,Pmrbeta,RGD1311710
    Uniprot AccessionQ8TEZ7
    Uniprot Entry NamePAQR8_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000170915
    Target ClassificationN/A

    The target: PAQR8, gene name: PAQR8, also named as C6orf33, LMPB1, MPRB. Predicted to enable steroid binding activity and steroid hormone receptor activity. Predicted to be involved in response to steroid hormone. Located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.