Anti-PCD10/ PCDH10/ OL-PCDH monoclonal antibody

Anti-PCD10/ PCDH10/ OL-PCDH antibody for FACS & in-vivo assay

Target products collectionGo to PCDH10/PCDH10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1325-Ab-1/ GM-Tg-hg-MP1325-Ab-2Anti-Human PCDH10 monoclonal antibodyHuman
GM-Tg-rg-MP1325-Ab-1/ GM-Tg-rg-MP1325-Ab-2Anti-Rat PCDH10 monoclonal antibodyRat
GM-Tg-mg-MP1325-Ab-1/ GM-Tg-mg-MP1325-Ab-2Anti-Mouse PCDH10 monoclonal antibodyMouse
GM-Tg-cynog-MP1325-Ab-1/ GM-Tg-cynog-MP1325-Ab-2Anti-Cynomolgus/ Rhesus macaque PCDH10 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1325-Ab-1/ GM-Tg-felg-MP1325-Ab-2Anti-Feline PCDH10 monoclonal antibodyFeline
GM-Tg-cang-MP1325-Ab-1/ GM-Tg-cang-MP1325-Ab-2Anti-Canine PCDH10 monoclonal antibodyCanine
GM-Tg-bovg-MP1325-Ab-1/ GM-Tg-bovg-MP1325-Ab-2Anti-Bovine PCDH10 monoclonal antibodyBovine
GM-Tg-equg-MP1325-Ab-1/ GM-Tg-equg-MP1325-Ab-2Anti-Equine PCDH10 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1325-Ab-1/ GM-Tg-hg-MP1325-Ab-2; GM-Tg-rg-MP1325-Ab-1/ GM-Tg-rg-MP1325-Ab-2;
GM-Tg-mg-MP1325-Ab-1/ GM-Tg-mg-MP1325-Ab-2; GM-Tg-cynog-MP1325-Ab-1/ GM-Tg-cynog-MP1325-Ab-2;
GM-Tg-felg-MP1325-Ab-1/ GM-Tg-felg-MP1325-Ab-2; GM-Tg-cang-MP1325-Ab-1/ GM-Tg-cang-MP1325-Ab-2;
GM-Tg-bovg-MP1325-Ab-1/ GM-Tg-bovg-MP1325-Ab-2; GM-Tg-equg-MP1325-Ab-1/ GM-Tg-equg-MP1325-Ab-2
Products NameAnti-PCDH10 monoclonal antibody
Formatmab
Target NamePCDH10
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PCDH10 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PCD10/ PCDH10/ OL-PCDH VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1325
    Target NamePCDH10
    Gene ID57575,18526,361943,695100,102156925,101099877,531875,100071688
    Gene Symbol and Synonyms6430521D13Rik,6430703F07Rik,mKIAA1400,OL-pc,OL-PCDH,PCDH10,PCDH19,RGD1565811
    Uniprot AccessionQ9P2E7
    Uniprot Entry NamePCD10_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000138650
    Target ClassificationN/A

    The target: PCDH10, gene name: PCDH10, also named as OL-PCDH, PCDH19. This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.