Anti-PCDH1/ PC42/ PCDH42 monoclonal antibody

Anti-PCDH1/ PC42/ PCDH42 antibody for FACS & in-vivo assay

Target products collectionGo to PCDH1/PCDH1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1326-Ab-1/ GM-Tg-hg-MP1326-Ab-2Anti-Human PCDH1 monoclonal antibodyHuman
GM-Tg-rg-MP1326-Ab-1/ GM-Tg-rg-MP1326-Ab-2Anti-Rat PCDH1 monoclonal antibodyRat
GM-Tg-mg-MP1326-Ab-1/ GM-Tg-mg-MP1326-Ab-2Anti-Mouse PCDH1 monoclonal antibodyMouse
GM-Tg-cynog-MP1326-Ab-1/ GM-Tg-cynog-MP1326-Ab-2Anti-Cynomolgus/ Rhesus macaque PCDH1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1326-Ab-1/ GM-Tg-felg-MP1326-Ab-2Anti-Feline PCDH1 monoclonal antibodyFeline
GM-Tg-cang-MP1326-Ab-1/ GM-Tg-cang-MP1326-Ab-2Anti-Canine PCDH1 monoclonal antibodyCanine
GM-Tg-bovg-MP1326-Ab-1/ GM-Tg-bovg-MP1326-Ab-2Anti-Bovine PCDH1 monoclonal antibodyBovine
GM-Tg-equg-MP1326-Ab-1/ GM-Tg-equg-MP1326-Ab-2Anti-Equine PCDH1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1326-Ab-1/ GM-Tg-hg-MP1326-Ab-2; GM-Tg-rg-MP1326-Ab-1/ GM-Tg-rg-MP1326-Ab-2;
GM-Tg-mg-MP1326-Ab-1/ GM-Tg-mg-MP1326-Ab-2; GM-Tg-cynog-MP1326-Ab-1/ GM-Tg-cynog-MP1326-Ab-2;
GM-Tg-felg-MP1326-Ab-1/ GM-Tg-felg-MP1326-Ab-2; GM-Tg-cang-MP1326-Ab-1/ GM-Tg-cang-MP1326-Ab-2;
GM-Tg-bovg-MP1326-Ab-1/ GM-Tg-bovg-MP1326-Ab-2; GM-Tg-equg-MP1326-Ab-1/ GM-Tg-equg-MP1326-Ab-2
Products NameAnti-PCDH1 monoclonal antibody
Formatmab
Target NamePCDH1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PCDH1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PCDH1/ PC42/ PCDH42 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1326
    Target NamePCDH1
    Gene ID5097,75599,307481,106998973,100856703,101080508,509388,100072165
    Gene Symbol and Synonyms2010005A06Rik,PC42,PCDH1,PCDH42
    Uniprot AccessionQ08174
    Uniprot Entry NamePCDH1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseIgA glomerulonephritis
    Gene EnsemblENSG00000156453
    Target ClassificationN/A

    The target: PCDH1, gene name: PCDH1, also named as PC42, PCDH42. This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.