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Anti-PC11X/ PCDH11X/ PCDH-X monoclonal antibody
Anti-PC11X/ PCDH11X/ PCDH-X antibody for FACS & in-vivo assay
Go to PCDH11X/PCDH11X products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1327-Ab-1/ GM-Tg-hg-MP1327-Ab-2 | Anti-Human PCDH11X monoclonal antibody | Human |
| GM-Tg-rg-MP1327-Ab-1/ GM-Tg-rg-MP1327-Ab-2 | Anti-Rat PCDH11X monoclonal antibody | Rat |
| GM-Tg-mg-MP1327-Ab-1/ GM-Tg-mg-MP1327-Ab-2 | Anti-Mouse PCDH11X monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1327-Ab-1/ GM-Tg-cynog-MP1327-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PCDH11X monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1327-Ab-1/ GM-Tg-felg-MP1327-Ab-2 | Anti-Feline PCDH11X monoclonal antibody | Feline |
| GM-Tg-cang-MP1327-Ab-1/ GM-Tg-cang-MP1327-Ab-2 | Anti-Canine PCDH11X monoclonal antibody | Canine |
| GM-Tg-bovg-MP1327-Ab-1/ GM-Tg-bovg-MP1327-Ab-2 | Anti-Bovine PCDH11X monoclonal antibody | Bovine |
| GM-Tg-equg-MP1327-Ab-1/ GM-Tg-equg-MP1327-Ab-2 | Anti-Equine PCDH11X monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1327-Ab-1/ GM-Tg-hg-MP1327-Ab-2; GM-Tg-rg-MP1327-Ab-1/ GM-Tg-rg-MP1327-Ab-2; GM-Tg-mg-MP1327-Ab-1/ GM-Tg-mg-MP1327-Ab-2; GM-Tg-cynog-MP1327-Ab-1/ GM-Tg-cynog-MP1327-Ab-2; GM-Tg-felg-MP1327-Ab-1/ GM-Tg-felg-MP1327-Ab-2; GM-Tg-cang-MP1327-Ab-1/ GM-Tg-cang-MP1327-Ab-2; GM-Tg-bovg-MP1327-Ab-1/ GM-Tg-bovg-MP1327-Ab-2; GM-Tg-equg-MP1327-Ab-1/ GM-Tg-equg-MP1327-Ab-2 |
| Products Name | Anti-PCDH11X monoclonal antibody |
| Format | mab |
| Target Name | PCDH11X |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PCDH11X benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PC11X/ PCDH11X/ PCDH-X VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP1327 |
| Target Name | PCDH11X |
| Gene ID | 27328,245578,317204,696659,101099279,538674,100071674 |
| Gene Symbol and Synonyms | PCDH-X,PCDH-Y,PCDH11,PCDH11X,PCDH11Y,PCDH22,PCDHX,PCDHX11,PPP1R119,RGD1562864 |
| Uniprot Accession | Q9BZA7 |
| Uniprot Entry Name | PC11X_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000102290 |
| Target Classification | N/A |
The target: PCDH11X, gene name: PCDH11X, also named as PCDH-X, PCDH-Y, PCDH11, PCDH11Y, PCDH22, PCDHX, PPP1R119. This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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