Anti-PCDH7/ BH-Pcdh/ BHPCDH monoclonal antibody

Anti-PCDH7/ BH-Pcdh/ BHPCDH antibody for FACS & in-vivo assay

Target products collectionGo to PCDH7/PCDH7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1333-Ab-1/ GM-Tg-hg-MP1333-Ab-2Anti-Human PCDH7 monoclonal antibodyHuman
GM-Tg-rg-MP1333-Ab-1/ GM-Tg-rg-MP1333-Ab-2Anti-Rat PCDH7 monoclonal antibodyRat
GM-Tg-mg-MP1333-Ab-1/ GM-Tg-mg-MP1333-Ab-2Anti-Mouse PCDH7 monoclonal antibodyMouse
GM-Tg-cynog-MP1333-Ab-1/ GM-Tg-cynog-MP1333-Ab-2Anti-Cynomolgus/ Rhesus macaque PCDH7 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1333-Ab-1/ GM-Tg-felg-MP1333-Ab-2Anti-Feline PCDH7 monoclonal antibodyFeline
GM-Tg-cang-MP1333-Ab-1/ GM-Tg-cang-MP1333-Ab-2Anti-Canine PCDH7 monoclonal antibodyCanine
GM-Tg-bovg-MP1333-Ab-1/ GM-Tg-bovg-MP1333-Ab-2Anti-Bovine PCDH7 monoclonal antibodyBovine
GM-Tg-equg-MP1333-Ab-1/ GM-Tg-equg-MP1333-Ab-2Anti-Equine PCDH7 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1333-Ab-1/ GM-Tg-hg-MP1333-Ab-2; GM-Tg-rg-MP1333-Ab-1/ GM-Tg-rg-MP1333-Ab-2;
GM-Tg-mg-MP1333-Ab-1/ GM-Tg-mg-MP1333-Ab-2; GM-Tg-cynog-MP1333-Ab-1/ GM-Tg-cynog-MP1333-Ab-2;
GM-Tg-felg-MP1333-Ab-1/ GM-Tg-felg-MP1333-Ab-2; GM-Tg-cang-MP1333-Ab-1/ GM-Tg-cang-MP1333-Ab-2;
GM-Tg-bovg-MP1333-Ab-1/ GM-Tg-bovg-MP1333-Ab-2; GM-Tg-equg-MP1333-Ab-1/ GM-Tg-equg-MP1333-Ab-2
Products NameAnti-PCDH7 monoclonal antibody
Formatmab
Target NamePCDH7
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PCDH7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PCDH7/ BH-Pcdh/ BHPCDH VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1333
    Target NamePCDH7
    Gene ID5099,54216,360942,696011,488843,102902647,514537,100065979
    Gene Symbol and SynonymsBH-Pcdh,BHPCDH,PCDH7,PPP1R120
    Uniprot AccessionO60245
    Uniprot Entry NamePCDH7_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseCancer
    Gene EnsemblENSG00000169851
    Target ClassificationTumor-associated antigen (TAA)

    The target: PCDH7, gene name: PCDH7, also named as BH-Pcdh, BHPCDH, PPP1R120. This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.