Anti-PCDH9 monoclonal antibody

Anti-PCDH9 antibody for FACS & in-vivo assay

Target products collectionGo to PCDH9/PCDH9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1335-Ab-1/ GM-Tg-hg-MP1335-Ab-2Anti-Human PCDH9 monoclonal antibodyHuman
GM-Tg-rg-MP1335-Ab-1/ GM-Tg-rg-MP1335-Ab-2Anti-Rat PCDH9 monoclonal antibodyRat
GM-Tg-mg-MP1335-Ab-1/ GM-Tg-mg-MP1335-Ab-2Anti-Mouse PCDH9 monoclonal antibodyMouse
GM-Tg-cynog-MP1335-Ab-1/ GM-Tg-cynog-MP1335-Ab-2Anti-Cynomolgus/ Rhesus macaque PCDH9 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1335-Ab-1/ GM-Tg-felg-MP1335-Ab-2Anti-Feline PCDH9 monoclonal antibodyFeline
GM-Tg-cang-MP1335-Ab-1/ GM-Tg-cang-MP1335-Ab-2Anti-Canine PCDH9 monoclonal antibodyCanine
GM-Tg-bovg-MP1335-Ab-1/ GM-Tg-bovg-MP1335-Ab-2Anti-Bovine PCDH9 monoclonal antibodyBovine
GM-Tg-equg-MP1335-Ab-1/ GM-Tg-equg-MP1335-Ab-2Anti-Equine PCDH9 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1335-Ab-1/ GM-Tg-hg-MP1335-Ab-2; GM-Tg-rg-MP1335-Ab-1/ GM-Tg-rg-MP1335-Ab-2;
GM-Tg-mg-MP1335-Ab-1/ GM-Tg-mg-MP1335-Ab-2; GM-Tg-cynog-MP1335-Ab-1/ GM-Tg-cynog-MP1335-Ab-2;
GM-Tg-felg-MP1335-Ab-1/ GM-Tg-felg-MP1335-Ab-2; GM-Tg-cang-MP1335-Ab-1/ GM-Tg-cang-MP1335-Ab-2;
GM-Tg-bovg-MP1335-Ab-1/ GM-Tg-bovg-MP1335-Ab-2; GM-Tg-equg-MP1335-Ab-1/ GM-Tg-equg-MP1335-Ab-2
Products NameAnti-PCDH9 monoclonal antibody
Formatmab
Target NamePCDH9
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PCDH9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PCDH9 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1335
    Target NamePCDH9
    Gene ID5101,211712,306091,677696,476942,101099519,509935,100051875
    Gene Symbol and SynonymsPCDH9
    Uniprot AccessionQ9HC56
    Uniprot Entry NamePCDH9_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000184226
    Target ClassificationN/A

    The target: PCDH9, gene name: PCDH9, also named as . This gene encodes a member of the protocadherin family, and cadherin superfamily, of transmembrane proteins containing cadherin domains. These proteins mediate cell adhesion in neural tissues in the presence of calcium. The encoded protein may be involved in signaling at neuronal synaptic junctions. Sharing a characteristic with other protocadherin genes, this gene has a notably large exon that encodes multiple cadherin domains and a transmembrane region. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Nov 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.