Anti-PIANP/ C12orf53/ LEDA1 monoclonal antibody

Anti-PIANP/ C12orf53/ LEDA1 antibody for FACS & in-vivo assay

Target products collectionGo to PIANP/PIANP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1364-Ab-1/ GM-Tg-hg-MP1364-Ab-2Anti-Human PIANP monoclonal antibodyHuman
GM-Tg-rg-MP1364-Ab-1/ GM-Tg-rg-MP1364-Ab-2Anti-Rat PIANP monoclonal antibodyRat
GM-Tg-mg-MP1364-Ab-1/ GM-Tg-mg-MP1364-Ab-2Anti-Mouse PIANP monoclonal antibodyMouse
GM-Tg-cynog-MP1364-Ab-1/ GM-Tg-cynog-MP1364-Ab-2Anti-Cynomolgus/ Rhesus macaque PIANP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1364-Ab-1/ GM-Tg-felg-MP1364-Ab-2Anti-Feline PIANP monoclonal antibodyFeline
GM-Tg-cang-MP1364-Ab-1/ GM-Tg-cang-MP1364-Ab-2Anti-Canine PIANP monoclonal antibodyCanine
GM-Tg-bovg-MP1364-Ab-1/ GM-Tg-bovg-MP1364-Ab-2Anti-Bovine PIANP monoclonal antibodyBovine
GM-Tg-equg-MP1364-Ab-1/ GM-Tg-equg-MP1364-Ab-2Anti-Equine PIANP monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1364-Ab-1/ GM-Tg-hg-MP1364-Ab-2; GM-Tg-rg-MP1364-Ab-1/ GM-Tg-rg-MP1364-Ab-2;
GM-Tg-mg-MP1364-Ab-1/ GM-Tg-mg-MP1364-Ab-2; GM-Tg-cynog-MP1364-Ab-1/ GM-Tg-cynog-MP1364-Ab-2;
GM-Tg-felg-MP1364-Ab-1/ GM-Tg-felg-MP1364-Ab-2; GM-Tg-cang-MP1364-Ab-1/ GM-Tg-cang-MP1364-Ab-2;
GM-Tg-bovg-MP1364-Ab-1/ GM-Tg-bovg-MP1364-Ab-2; GM-Tg-equg-MP1364-Ab-1/ GM-Tg-equg-MP1364-Ab-2
Products NameAnti-PIANP monoclonal antibody
Formatmab
Target NamePIANP
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PIANP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PIANP/ C12orf53/ LEDA1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1364
    Target NamePIANP
    Gene ID196500,319352,312711,713548,611639,101083602,614601,100052384
    Gene Symbol and SynonymsC11H12orf53,C12orf53,C27H12orf53,C530028O21Rik,C5H12orf53,leda-1,LEDA1,PANP,PIANP,RGD1304952
    Uniprot AccessionQ8IYJ0,Q5U2P6
    Uniprot Entry NamePIANP_HUMAN,PIANP_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000139200
    Target ClassificationN/A

    The target: PIANP, gene name: PIANP, also named as C12orf53, LEDA1, PANP, leda-1. This gene encodes a ligand for the paired immunoglobin-like type 2 receptor alpha, and so may be involved in immune regulation. Alternate splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Sep 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.