Anti-PIGY/ HPMRS6/ PIG-Y monoclonal antibody

Anti-PIGY/ HPMRS6/ PIG-Y antibody for FACS & in-vivo assay

Target products collectionGo to PIGY/PIGY products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1369-Ab-1/ GM-Tg-hg-MP1369-Ab-2Anti-Human PIGY monoclonal antibodyHuman
GM-Tg-rg-MP1369-Ab-1/ GM-Tg-rg-MP1369-Ab-2Anti-Rat PIGY monoclonal antibodyRat
GM-Tg-mg-MP1369-Ab-1/ GM-Tg-mg-MP1369-Ab-2Anti-Mouse PIGY monoclonal antibodyMouse
GM-Tg-cynog-MP1369-Ab-1/ GM-Tg-cynog-MP1369-Ab-2Anti-Cynomolgus/ Rhesus macaque PIGY monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1369-Ab-1/ GM-Tg-felg-MP1369-Ab-2Anti-Feline PIGY monoclonal antibodyFeline
GM-Tg-cang-MP1369-Ab-1/ GM-Tg-cang-MP1369-Ab-2Anti-Canine PIGY monoclonal antibodyCanine
GM-Tg-bovg-MP1369-Ab-1/ GM-Tg-bovg-MP1369-Ab-2Anti-Bovine PIGY monoclonal antibodyBovine
GM-Tg-equg-MP1369-Ab-1/ GM-Tg-equg-MP1369-Ab-2Anti-Equine PIGY monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1369-Ab-1/ GM-Tg-hg-MP1369-Ab-2; GM-Tg-rg-MP1369-Ab-1/ GM-Tg-rg-MP1369-Ab-2;
GM-Tg-mg-MP1369-Ab-1/ GM-Tg-mg-MP1369-Ab-2; GM-Tg-cynog-MP1369-Ab-1/ GM-Tg-cynog-MP1369-Ab-2;
GM-Tg-felg-MP1369-Ab-1/ GM-Tg-felg-MP1369-Ab-2; GM-Tg-cang-MP1369-Ab-1/ GM-Tg-cang-MP1369-Ab-2;
GM-Tg-bovg-MP1369-Ab-1/ GM-Tg-bovg-MP1369-Ab-2; GM-Tg-equg-MP1369-Ab-1/ GM-Tg-equg-MP1369-Ab-2
Products NameAnti-PIGY monoclonal antibody
Formatmab
Target NamePIGY
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PIGY benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PIGY/ HPMRS6/ PIG-Y VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1369
    Target NamePIGY
    Gene ID84992,100426107,487853,102901476,514374,100629775
    Gene Symbol and SynonymsHPMRS6,PIG-Y,PIGY
    Uniprot AccessionQ3MUY2,P0C1N9
    Uniprot Entry NamePIGY_HUMAN,PIGY_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000255072
    Target ClassificationN/A

    The target: PIGY, gene name: PIGY, also named as HPMRS6, PIG-Y. The protein encoded by this gene is part of the GPI-N-acetylglucosaminyltransferase (GIP-GnT) complex which initiates the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is synthesized in the endoplasmic reticulum and serves as an anchor for many surface proteins. Proteins containing GPI anchors can have an important role in cell-cell interactions. The transcript for this gene is bicistronic. The downstream open reading frame encodes this GPI-GnT complex protein, while the upstream open reading frame encodes a protein with unknown function, as represented by GeneID:100996939. [provided by RefSeq, Aug 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.