Anti-P3IP1/ PIK3IP1/ HGFL monoclonal antibody

Anti-P3IP1/ PIK3IP1/ HGFL antibody for FACS & in-vivo assay

Target products collectionGo to PIK3IP1/PIK3IP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1370-Ab-1/ GM-Tg-hg-MP1370-Ab-2Anti-Human PIK3IP1 monoclonal antibodyHuman
GM-Tg-rg-MP1370-Ab-1/ GM-Tg-rg-MP1370-Ab-2Anti-Rat PIK3IP1 monoclonal antibodyRat
GM-Tg-mg-MP1370-Ab-1/ GM-Tg-mg-MP1370-Ab-2Anti-Mouse PIK3IP1 monoclonal antibodyMouse
GM-Tg-cynog-MP1370-Ab-1/ GM-Tg-cynog-MP1370-Ab-2Anti-Cynomolgus/ Rhesus macaque PIK3IP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1370-Ab-1/ GM-Tg-felg-MP1370-Ab-2Anti-Feline PIK3IP1 monoclonal antibodyFeline
GM-Tg-cang-MP1370-Ab-1/ GM-Tg-cang-MP1370-Ab-2Anti-Canine PIK3IP1 monoclonal antibodyCanine
GM-Tg-bovg-MP1370-Ab-1/ GM-Tg-bovg-MP1370-Ab-2Anti-Bovine PIK3IP1 monoclonal antibodyBovine
GM-Tg-equg-MP1370-Ab-1/ GM-Tg-equg-MP1370-Ab-2Anti-Equine PIK3IP1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1370-Ab-1/ GM-Tg-hg-MP1370-Ab-2; GM-Tg-rg-MP1370-Ab-1/ GM-Tg-rg-MP1370-Ab-2;
GM-Tg-mg-MP1370-Ab-1/ GM-Tg-mg-MP1370-Ab-2; GM-Tg-cynog-MP1370-Ab-1/ GM-Tg-cynog-MP1370-Ab-2;
GM-Tg-felg-MP1370-Ab-1/ GM-Tg-felg-MP1370-Ab-2; GM-Tg-cang-MP1370-Ab-1/ GM-Tg-cang-MP1370-Ab-2;
GM-Tg-bovg-MP1370-Ab-1/ GM-Tg-bovg-MP1370-Ab-2; GM-Tg-equg-MP1370-Ab-1/ GM-Tg-equg-MP1370-Ab-2
Products NameAnti-PIK3IP1 monoclonal antibody
Formatmab
Target NamePIK3IP1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PIK3IP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species P3IP1/ PIK3IP1/ HGFL VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1370
    Target NamePIK3IP1
    Gene ID113791,216505,305472,716694,486364,101097180,512082,100063270
    Gene Symbol and Synonyms1500004A08Rik,5830455E04Rik,Crkd,HGFL,hHGFL(S),PIK3IP1,RGD1311203,TrIP,zgc:66482
    Uniprot AccessionQ96FE7,Q56A20,Q1RMT9
    Uniprot Entry NameP3IP1_HUMAN,P3IP1_RAT,P3IP1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000100100
    Target ClassificationN/A

    The target: PIK3IP1, gene name: PIK3IP1, also named as HGFL, hHGFL(S). Enables phosphatidylinositol 3-kinase catalytic subunit binding activity. Involved in negative regulation of phosphatidylinositol 3-kinase activity and negative regulation of phosphatidylinositol 3-kinase signaling. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.