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Anti-PLS4/ PLSCR4/ TRA1 monoclonal antibody
Anti-PLS4/ PLSCR4/ TRA1 antibody for FACS & in-vivo assay
Go to PLSCR4/PLSCR4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1384-Ab-1/ GM-Tg-hg-MP1384-Ab-2 | Anti-Human PLSCR4 monoclonal antibody | Human |
| GM-Tg-rg-MP1384-Ab-1/ GM-Tg-rg-MP1384-Ab-2 | Anti-Rat PLSCR4 monoclonal antibody | Rat |
| GM-Tg-mg-MP1384-Ab-1/ GM-Tg-mg-MP1384-Ab-2 | Anti-Mouse PLSCR4 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1384-Ab-1/ GM-Tg-cynog-MP1384-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PLSCR4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1384-Ab-1/ GM-Tg-felg-MP1384-Ab-2 | Anti-Feline PLSCR4 monoclonal antibody | Feline |
| GM-Tg-cang-MP1384-Ab-1/ GM-Tg-cang-MP1384-Ab-2 | Anti-Canine PLSCR4 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1384-Ab-1/ GM-Tg-bovg-MP1384-Ab-2 | Anti-Bovine PLSCR4 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1384-Ab-1/ GM-Tg-equg-MP1384-Ab-2 | Anti-Equine PLSCR4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1384-Ab-1/ GM-Tg-hg-MP1384-Ab-2; GM-Tg-rg-MP1384-Ab-1/ GM-Tg-rg-MP1384-Ab-2; GM-Tg-mg-MP1384-Ab-1/ GM-Tg-mg-MP1384-Ab-2; GM-Tg-cynog-MP1384-Ab-1/ GM-Tg-cynog-MP1384-Ab-2; GM-Tg-felg-MP1384-Ab-1/ GM-Tg-felg-MP1384-Ab-2; GM-Tg-cang-MP1384-Ab-1/ GM-Tg-cang-MP1384-Ab-2; GM-Tg-bovg-MP1384-Ab-1/ GM-Tg-bovg-MP1384-Ab-2; GM-Tg-equg-MP1384-Ab-1/ GM-Tg-equg-MP1384-Ab-2 |
| Products Name | Anti-PLSCR4 monoclonal antibody |
| Format | mab |
| Target Name | PLSCR4 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PLSCR4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PLS4/ PLSCR4/ TRA1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP003169 | human PLSCR4 Lentivirus particle |
| ORF Viral Vector | pGMLP003169 | human PLSCR4 Lentivirus plasmid |
| ORF Viral Vector | pGMAAV000103 | mouse Plscr4 AAV plasmid |
| ORF Viral Vector | vGMAAV000103 | mouse Plscr4 AAV particle |
Target information
| Target ID | GM-MP1384 |
| Target Name | PLSCR4 |
| Gene ID | 57088,235527,300900,713430,611495,101085489,539290,100060925 |
| Gene Symbol and Synonyms | Pls4,PLSCR4,TRA1 |
| Uniprot Accession | Q9NRQ2 |
| Uniprot Entry Name | PLS4_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000114698 |
| Target Classification | N/A |
The target: PLSCR4, gene name: PLSCR4, also named as TRA1. Enables CD4 receptor binding activity and enzyme binding activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to act upstream of or within cellular response to lipopolysaccharide. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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