Anti-PLXA1/ PLXNA1/ NOV monoclonal antibody

Anti-PLXA1/ PLXNA1/ NOV antibody for FACS & in-vivo assay

Target products collectionGo to PLXNA1/PLXNA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1386-Ab-1/ GM-Tg-hg-MP1386-Ab-2Anti-Human PLXNA1 monoclonal antibodyHuman
GM-Tg-rg-MP1386-Ab-1/ GM-Tg-rg-MP1386-Ab-2Anti-Rat PLXNA1 monoclonal antibodyRat
GM-Tg-mg-MP1386-Ab-1/ GM-Tg-mg-MP1386-Ab-2Anti-Mouse PLXNA1 monoclonal antibodyMouse
GM-Tg-cynog-MP1386-Ab-1/ GM-Tg-cynog-MP1386-Ab-2Anti-Cynomolgus/ Rhesus macaque PLXNA1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1386-Ab-1/ GM-Tg-felg-MP1386-Ab-2Anti-Feline PLXNA1 monoclonal antibodyFeline
GM-Tg-cang-MP1386-Ab-1/ GM-Tg-cang-MP1386-Ab-2Anti-Canine PLXNA1 monoclonal antibodyCanine
GM-Tg-bovg-MP1386-Ab-1/ GM-Tg-bovg-MP1386-Ab-2Anti-Bovine PLXNA1 monoclonal antibodyBovine
GM-Tg-equg-MP1386-Ab-1/ GM-Tg-equg-MP1386-Ab-2Anti-Equine PLXNA1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1386-Ab-1/ GM-Tg-hg-MP1386-Ab-2; GM-Tg-rg-MP1386-Ab-1/ GM-Tg-rg-MP1386-Ab-2;
GM-Tg-mg-MP1386-Ab-1/ GM-Tg-mg-MP1386-Ab-2; GM-Tg-cynog-MP1386-Ab-1/ GM-Tg-cynog-MP1386-Ab-2;
GM-Tg-felg-MP1386-Ab-1/ GM-Tg-felg-MP1386-Ab-2; GM-Tg-cang-MP1386-Ab-1/ GM-Tg-cang-MP1386-Ab-2;
GM-Tg-bovg-MP1386-Ab-1/ GM-Tg-bovg-MP1386-Ab-2; GM-Tg-equg-MP1386-Ab-1/ GM-Tg-equg-MP1386-Ab-2
Products NameAnti-PLXNA1 monoclonal antibody
Formatmab
Target NamePLXNA1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PLXNA1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PLXA1/ PLXNA1/ NOV VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1386
    Target NamePLXNA1
    Gene ID5361,18844,362398,716805,100688869,101090680,531240,100060411
    Gene Symbol and Synonyms2600013D04Rik,DWOPNED,mKIAA4053,NOV,NOVP,PlexA1,PLEXIN-A1,PLXN1,PLXNA1,RGD1560871
    Uniprot AccessionQ9UIW2
    Uniprot Entry NamePLXA1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000114554
    Target ClassificationN/A

    The target: PLXNA1, gene name: PLXNA1, also named as NOV, NOVP, PLEXIN-A1, PLXN1. Predicted to enable semaphorin receptor activity. Predicted to be involved in several processes, including generation of neurons; regulation of GTPase activity; and regulation of cell shape. Predicted to act upstream of or within dichotomous subdivision of terminal units involved in salivary gland branching; neuron projection morphogenesis; and regulation of smooth muscle cell migration. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.